Educational Background
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2005.92009.6
Nankai University
Pharmacy
Bachelor's Degree in Science
Undergraduate (Bachelor’s degree)
Supervisor: Prof. Wei Zhao
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2009.92014.6
Peking University
Physical Chemistry
Doctoral Degree in Science
Doctoral Study
Supervisor: Prof. Yundong Wu, Prof. Olaf G. Wiest
Research Interests: Theoretical Studies on Enzyme Mechanism and Protein-Protein Interaction
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Personal Information
陈凯，男，副教授、硕士生导师。2009年本科毕业于南开大学药学院，2014年博士毕业于北京大学化学与分子工程学院，师从吴云东院士和Olaf G. Wiest教授，攻读博士期间主要从事表观遗传学调控的理论机制研究。2015年作为师资博士后加入华南理工大学祝诗发教授团队，专注于过渡金属催化不饱和烃环异构化反应机制方面的研究。2019年入职中南大学化学化工学院制药工程系，2022年晋升副教授。近年来，致力于计算化学与有机化学结合研究有机化学反应的机制和新型功能分子的设计，在可见光促进的烯烃双官能团化、杂环甲基化、以及含氟化合物的脱氟官能团化等领域取得一些进展。先后主持国家自然科学基金青年项目、湖南省自然科学基金、广东省自然科学基金、博士后基金面上项目和特殊资助项目等。以第一作者或通讯作者在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、ACS Catal、Chem、Org. Lett.、《中国科学.化学》等权威期刊发表文章60余篇。
ORCID: 0000-0003-1012-0383
近年来发表的主要论文
2023
Photosensitized Vicinal Sulfonylamination of Alkenes with Oxime Ester and DABCO·(SO2)2, Chu-Ping Yuan, Yu Zheng, Zhen-Zhen Xie, Ke-Yi Deng, Hong-Bin Chen, Hao-Yue Xiang, Kai Chen,* Hua Yang*, Org. Lett. 2023, doi: 10.1021/acs.orglett.3c00559
1, 2‐Difunctionalization of Acetylene Enabled by Light, Shiwei Lü, Zipeng Wang, Xiang Gao, Kai Chen,* Shifa Zhu,* Angew. Chem. Int. Ed. 2023, doi: 10.1002/ange.202300268
2022
Photoredox‐Catalyzed Deoxygenation of Hexafluoroacetone Hydrate Enables Hydroxypolyfluoroalkylation of Alkenes, Zhen‐Zhen Xie, Yu Zheng, Chu‐Ping Yuan, Jian‐Ping Guan, Zhi‐Peng Ye, Jun‐An Xiao, Hao‐Yue Xiang, Kai Chen,* Xiao‐Qing Chen,* Hua Yang, Angew. Chem. Int. Ed. 2022, 61, e202211035
Regioselective Access to Vicinal Diamines by Metal‐Free Photosensitized Amidylimination of Alkenes with Oxime Esters, Yu Zheng, Zhu‐Jun Wang, Zhi‐Peng Ye, Kai Tang, Zhen‐Zhen Xie, Jun‐An Xiao, Hao‐Yue Xiang, Kai Chen,* Xiao‐Qing Chen,* Hua Yang,* Angew. Chem. Int. Ed. 2022, 61, e202212292
Photoredox-catalysed chlorination of quinoxalin-2 (1 H)-ones enabled by using CHCl3 as a chlorine source, Mei-Chun Wu, Ming-Zhi Li, Jia-Yi Chen, Jun-An Xiao, Hao-Yue Xiang, Kai Chen,* Hua Yang*, Chem. Commun. 2022, 58, 11591-11594.
Rh2(II)-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor–donor carbenes, Dong Zhu, Tongxiang Cao, Kai Chen,* Shifa Zhu,* Chem. Sci. 2022, 13, 1992-2000.
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Associate Professor
Supervisor of Master's Candidates
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Date of Employment:2019-10-15
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School/Department:Chemistry and Chemical Engineering
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Education Level:PhD Graduate
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Business Address:化学化工学院435
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Sex:Male
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Degree:Doctoral degree
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Status:Employed
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Alma Mater:北京大学
- Discipline:Chemical Engineering and Technology
- Postal Address：55841dd629837794ce903782536a12dfc58a5b5abc200e7a05feaa465cda50bb83c5d705d27e43c7bfe9db160f36762d3d470aa2d6c8c71963db348eb97bfa65afaedb24e84d7d3e5dbf80969c66e2787bdc0ae530a37ef2f11f41317b3d16822f72f93773648e52257ab989610383c5aca5062a5d5bcd815423c96dbc6733a2
- Email：69578b6ea56805667096db1ff5034fa8d4a4a743546a5d3174620e9e1779dcd16cdc6553e5fa233921e9b16d24995125a0f0671462cd5dedff82e42526d48f75dca7915dc15b46c13fc1386b53ea496b28ae8c26584e6b1e8208cf166d06db148bceea2668e58e9230a1815159cfa79efc1207f8f6d455eaf5766e7b8c27b9c4
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