Bin Meng
Name of Research Group: Nano-Bio Technology Laboratory
Description of Research Group:Biomedical engineering, the most rapidly growing of engineering disciplines from a global perspective, is now playing an irreplaceable role in the enhancement of human lifespan and its quality. At our Nano-Bio Technology Laboratory, we explore multi-disciplinary research and cutting-edge technology so that we bridge medicine and technology. Specifically, we are dedicated to achieving similar success with polypeptide sequencing to what nanopore sequencing has done to DNA so that there will be a possibility that we understand the causes of protein primary structure related diseases better and consequently come up with a solution. Moreover, solid-state nanopores have huge potential in single cell secretion detection because significant clinical biomarkers can be selective thanks to nanopore's adjustable geometry. We are also interested in utilizing electron microscopy and atomic force microscopy in various biomedical applications, such as synthetic biology and virology, to aid clinic treatment.
Team members Introduction:Bin Meng, Ph.D. student (Class 2021) in Biomedical Engineering and Technology. He obtained his master’s degree in Cell Biology at the School of Basic Medical Sciences, Central South University, in June 2021. As a graduate, he was engaged in the study of the mechanism of multiple myeloma development and published two scientific papers in this field. He is proficient in various molecular biology experimental skills and eager to explore beyond that. His current research interest focuses single molecule protein sequencing by using nanopore sensors. Email: mengbin7@csu.edu.cn Publications: 1. NEK2 Induces Autophagy-mediated Bortezomib Resistance by Stabilizing Beclin-1 in Multiple Myeloma, Molecular Oncology, 2020; 14(4). 2. The molecular mechanism of targeted valine metabolism inducing apoptosis in multiple myeloma, under preparation.
