Impact Factor:2.615
Affiliation of Author(s):资源加工与生物工程学院
Journal:Transactions of Nonferrous Metals Society of China
Key Words:Leptospirillum ferriphilum; comparative genome; nitrogen fixation; intraspecific variation; recombination
Abstract:To reveal the intraspecific evolution of Leptospirillum ferriphilum isolates which thrived in industrial bioleaching ecosystems and acid mine drainages, genome sequences of L. ferriphilum YSK, L. ferriphilum DX and L. ferriphilum ZJ were determined to compare with complete genome of L. ferriphilum ML-04. The genome comparisons reveal that extensive intraspecific variation occurs in their genomes, and that the loss and insertion of novel gene blocks of probable phage origin may mostly contribute to heterogeneity of gene content among L. ferriphilum genomes. Surprisingly, a nif gene cluster is identified in L. ferriphilum YSK and L. ferriphilum ZJ genomes. Intensive analysis and further experiments indicate that the nif gene cluster in L. ferriphilum YSK inherits from ancestor rather than lateral gene transfer. Overall, results suggest that the population of L. ferriphilum undergoes frequent genetic recombination, resulting in many closely related genome types in recent evolution. The combinatorial processes profoundly shape their physiologies and provide the basis for adaptation to different niches.
Co-author:Liangfeng Xu, Xue Guo, Hui-dan Jiang, Xueduan Liu, Huaqun Yin, Yazi Liu*
First Author:Hongwei Liu
Indexed by:Journal paper
Document Type:J
Volume:30
Issue:6
Page Number:1635-1646
ISSN No.:1003-6326
Translation or Not:no