宋相志

有机及高分子化学系主任

教授 、研究生导师 、博士生导师

单位:化学化工学院

入职时间:2011年11月01日

曾获荣誉:教育部新世纪优秀人才、中南大学“升华”学者特聘教授

学位:博士学位

专业:化学

毕业院校:北京大学

电子邮件:

个人简历

●工作经历
2009-    中南大学化学化工学院(“升华学者”特聘教授、博士生导师)
2005-2009  哈佛大学罗兰研究所(Senior Research Scientist)
2003-2005  哈佛大学罗兰研究所(Postdoctoral Research Associate)
●教育经历
博士:1999-2002 北京大学化学与分子工程学院
硕士:1996-1999 大连理工大学化学与化工学院
学士:1992-1996 中国地质大学化学系

宋相志博士,教育部“新世纪优秀人才计划”获得者,中南大学“升华学者”特聘教授,博士生导师,中南大学化学化工学院化学系主任。从事有功能染料研究近20年,主要研究方向包括荧光染料、光疗药物、荧光探针分子的研发及生物医学应用,目前在Nature Commun.,J. Am. Chem.Soc., Anal. Chem.,J. Med. Chem., Chem. Commun.等国际学术刊物发表SCI论文50余篇。

招生学科:有机化学

代表性成果:
1.    Liu, Xingjiang; Li, Ying; Ren, Xiaojie; Yang, Qinwei; Su, Yuanan; He, Long; Song, Xiangzhi*, Methylated Chromenoquinoline Dyes: Synthesis, Optical Properties, and Application for Mitochondrial Labeling., Chemical Communications, 2018,54, 1509-1512.
2.    Yang, Lei; Su, Yuanan; Sha, Zhankui; Geng, Yani; Qi, Fengpei; Song, Xiangzhi*, A red-emitting fluorescent probe for hydrogen sulfide in living cells with a large Stokes shift. Organic & Biomolecular Chemistry, 2018,16, 1150-1156.
3.    Fang, Qian; Tian, Huihui; Yang, Lei; Chen, Song; Liu, Xingjiang; Song, Xiangzhi*, A thiocoumarin-based fluorescent probe for detection of hypochlorite with high selectivity over other typical desulfurizing agents (Hg2+/Ag+)., Sensors and Actuators, B: Chemical, 2018, 260, 146-155.
4.    Liu, Xingjiang; He, Long; Yang, Liu; Geng, Yani; Yang, Lei; Song, Xiangzhi*, . Iminocoumarin-based fluorescence probe for intracellular H2O2 detection with a red emission and a large Stokes shift., Sensors and Actuators, B: Chemical, 2018, 259, 803-808.
5.    Chen, Wenqiang; Yue, Xiuxiu; Zhang, Hui; Li, Wenxiu; Zhang, Liangliang; Xiao, Qi; Huang, Chusheng; Sheng, Jiarong; Song, Xiangzhi, Simultaneous Detection of Glutathione and Hydrogen Polysulfides from Different Emission Channels., Analytical Chemistry, 2017, 89(23), 12984-12991.
6.    Xingjiang Liu, Yuanan Su, Huihui Tian, Lei Yang, Hongyan Zhang, Xiangzhi Song* and James Foley, Ratiometric Fluorescent Probe for Lysosomal pH Measurement and Imaging in Living Cells Using Single-Wavelength Excitation. Analytical Chemsitry, 2017, 89(13), 7038-7045.  
7.    Xingjiang Liu,HuiHui Tian, Lei Yang, Yuanan Su, Man Guo and Xiangzhi Song*,  A sensitive and selective fluorescent probe for the detection of hydrogen peroxide with a red emission and a large Stokes shift. Sensors and Actuators B 255, 2018, 1160–1165.
8.    Xingjiang Liu, HuiHui Tian, Lei Yang, Yuanan Su,; Man Guo and Xiangzhi Song*, An ESIPT-based fluorescent probe for sensitive and selective detection of Cys/Hcy over GSH with a red emission and a large Stokes shift. Tetrahedron Letters, 2017, 58(33), 3209-3213.
9.    Xingjiang Liu, Fengpei Qi, Yuanan Su, Wenqiang Chen, Lei Yang and Xiangzhi Song*, A red emitting fluorescent probe for instantaneous sensing of thiophenol in both aqueous medium and living cells with a large Stokes shift. Journal of Materials Chemistry C, 2016, 4, 4320—4326.
10.    Wenqiang Chen, Hongchen Luo, Xingjiang Liu, James W. Foley,Xiangzhi Song*, A broadly applicable strategy for the fluorescence based detection and differentiation of glutathione and cysteine/homocysteine: Demonstration in-vitro and in-vivo. Analytical Chemistry, 2016,88 (7), 3638–3646.
11.    Wenqiang Chen, Qian Fang, Dalei Yang, Hongyan Zhang, Xiangzhi Song*, James Foley, Selective, Highly Sensitive Fluorescent Probe for the Detection of Sulfur Dioxide Derivatives in Aqueous and Biological Environments. Analytical Chemistry, 2015,87, 609-616.
12.    Xingjiang Liu, Qinwei Yang, Wenqiang Chen, Lingna Mo, Song Chen, Jiang Kang, Xiangzhi Song*, A ratiometric fluorescent probe for rapid, sensitive and selective detection of sulfur dioxide with large Stokes shifts by single wavelength excitation. Organic & Biomolecular Chemistry, 2015,13, 8663-8668.
13.    Wenqiang Chen, Song Chen, Bingjiang Zhou, Hongbo Wang, Xiangzhi Song*, Hongyan Zhang,* Highly selective red-emitting H2S fluorescent probe with a large Stokes shift. Dyes and Pigments, 2015,113, 596-601.
14.    Song Chen, Peng Hou, Xiangzhi Song*, A red-emitting fluorescent probe for imaging hydrogen sulphide with a large Stokes shift. Sensors And Actuators B-Chemical, 2015,221, 951-955.
15.    Wenqiang Chen, Hongchen Luo, Xingjiang Liu, Fengpei Qi, Dalei Yang, Xiangzhi Song*, A fluorescent probe emitting in near-infrared region for sensitive and selective detection of biothiols in both solution and living cells. Tetrahedron Letters, 2015,56, 7176-7179.
16.    Xingjiang Liu, Liu Yang, Li Gao, Wenqiang Chen, Fengpei Qi, Xiangzhi Song*, A phthalimide-based fluorescent probe for thiophenol detection in water samples and living cells with a large Stokes shift. Tetrahedron, 2015,71, 8285-8289.
17.    Peng Hou, Song Chen, Hongbo Wang, Jianxiu Wang, Kislon Voitchovsky, Xiangzhi Song*, An aqueous red emitting fluorescent fluoride sensing probe exhibiting a large Stokes shift and its application in cell imaging. Chemical Communications, 2014,50, 320-322.
18.    Yifei Han, Wenqiang Chen, Hongbo Wang,* Yingxue Yuan, Nana Wu, Xiangzhi Song*, Lan Yang, An AAA-DDD Triply Hydrogen-Bonded Complex Easily Accessibl

教育经历

[1]  1992.9-1996.6

中国地质大学 | 分析化学 | 学士学位 | 大学本科毕业

[2]  1996.9-1999.6

大连理工大学 | 精细化工 | 硕士学位 | 硕士研究生结业

[3]  1999.9-2002.6

北京大学 | 化学 | 博士学位 | 博士研究生毕业

工作经历

[1]  2009.9-至今

 化学化工学院 |  中南大学 |  系主任  教授

[2]  2005.3-2009.8

 Rowland Institute |  哈佛大学  Senior Research Scientist

[3]  2003.3-2005.2

 Rowland Institute |  哈佛大学  Postdoctoral Associate

研究方向

  • [1]   抗癌光疗药物

  • [2]   分子荧光探针

  • [3]   荧光染料的设计与合成