DOI number:10.1039/d0an01336f
Affiliation of Author(s):Central South University
Journal:royal society of chemisty
Abstract:DNA possesses various chemical and physical properties which make it important in biological analysis. The opportunity for DNA to ‘meet’ capillary-based microsystems is rapidly increasing owing to the expanding development of miniaturization. Novel capillary-based methods can provide favourable plat- forms for DNA–ligand interaction assay, DNA translocation study, DNA separation, DNA aptamer selec- tion, DNA amplification assay, and DNA digestion. Meanwhile, DNA exhibits great potential in the fabrica- tion of new capillary-based biosensors and enzymatic bioreactors. Moreover, DNA has received significant research interest in improving capillary electrophoresis (CE) performance. We focus on highlighting the advantages of combining DNA and capillary-based microsystems. The general trend presented in this review suggests that the ‘meeting’ has offered a stepping stone for the application of DNA and capillary- based microsystems in the field of analytical chemistry.
Volume:2021
Issue:146
Page Number:48-63
Translation or Not:no