学位:博士学位
学历:研究生(博士)毕业
职称:教授
所在单位:湘雅基础医学院
学术荣誉: 曾获荣誉:
中南大学教授,博士生/博士后导师,现任中南大学基础医学院病理学系/湘雅医院病理科副主任、分子病理诊断中心主任。病理学国家级精品课程主讲教师、病理学国家级资源共享课程主讲教师及基础医学形态学国家级教学团队、卫计委临床重点专科骨干成员,副主编及参编《病理学》全国高等学校医学规划教材及配套教材7本,人民卫生出版社国家医学教育题库病理学学科副主编,获校级教学成果奖8项;参与或主持了教育部教改项目、教育部修购专项资助项目、教育部985资助项目、国家自然科学基金及湖南省科技计划项目10项。发表本专业SCI论文90余篇。获湖南省自然科学奖三等奖一项。
Desheng Xiao, Ph.D., professor, PhD candidate/post-doctoral supervisor, Deputy Director of Department of Pathology, Basic Medical School/Xiangya Hospital, Central South University, Director of Molecular Pathology Diagnosis Center. The main teacher of national excellent pathology course and national resource sharing course, the national teaching team of basic medical Morphology, and the main member of National Health and Family Planning Commission key clinical specialty. Presided over or participated in 10 projects of national Natural Science Foundation of China and Natural Science Foundation of Hunan Province. Won the third prize of Natural Science award of Hunan Province (ranked the third). Published more than 90 SCI papers in this field. Concurrently hold the molecular pathology group member of the Chinese medical doctor association pathology branch, a member of the standing committee of the China medical equipment AI union pathology committee, the incoming chairman of hunan province medical association pathology professional committee, the chairman of hunan medical association pathology professional committee Younger Committee, the vice president of Hunan Medical Doctor Association Pathologist Branch, the vice director of hunan Clinicopathological Quality Control Center, a member of Hunan Anti-cancer Association Lung Cancer Professional Committee. and a review expert of the National Natural Science Foundation of China.
Role of non-coding RNAs and RNA modifiers in cancer therapy resistance
点击次数:
影响因子:5.134
所属单位:中南大学
教研室:病理学系
发表刊物:Mol Cancer
关键字:ncRNAs, RNA modifiers, Chemoresistance, Radioresistance
摘要:As the standard treatments for cancer, chemotherapy and radiotherapy have been widely applied to clinical practice worldwide. However, the resistance to cancer therapies is a major challenge in clinics and scientific research, resulting in tumor recurrence and metastasis. The mechanisms of therapy resistance are complicated and result from multiple factors. Among them, non-coding RNAs (ncRNAs), along with their modifiers, have been investigated to play key roles in regulating tumor development and mediating therapy resistance within various cancers, such as hepatocellular carcinoma, breast cancer, lung cancer, gastric cancer, etc. In this review, we attempt to elucidate the mechanisms underlying ncRNA/modifier-modulated resistance to chemotherapy and radiotherapy, providing some therapeutic potential points for future cancer treatment.
合写作者:Kai Xie, Honghua Zhou, Yuwei Wu, Chan Li, Yating Liu, Zhaoya Liu, Qian Xu
第一作者:Xinyi Zhang
论文类型:期刊论文
通讯作者:,Shuang Liu, Desheng Xiao, Yongguang Tao
学科门类:基础医学
文献类型:J
卷号:19(1)
页面范围:47
是否译文:否
发表时间:2020-01-01
收录刊物:SCI