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Photocatalytic intermolecular anti-Markovnikov hydroamination of unactivated alkenes with N-hydroxyphthalimide

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Release time:2021-07-02
DOI number:10.1039/D0QO01321H
Journal:Organic Chemistry Frontiers
Abstract:A visible-light-induced/phosphite-promoted anti-Markovnikov hydroamination of alkenes with N-hydroxyphthalimide was successfully realized, which was initiated by a proton-coupled electron transfer to enable direct cleavage of its N–O bond. Both experimental and computational studies were performed to probe the reaction mechanism. A wide range of alkenes, including vinyl ethers, silanes, and sulfides as well as electronically unbiased terminal and internal alkenes, were well tolerated in this hydroamination protocol.
Co-author:Yuan-Zhuo Hu
First Author:Zhi-Peng Ye
Indexed by:Journal paper
Correspondence Author:Peng-Ju Xia*, Kai Chen*, Hao-Yue Xiang*, Hua Yang*
Volume:8
Issue:2
Page Number:273-277
Translation or Not:no
Date of Publication:2020-11-09
Included Journals:SCI
Links to published journals:https://pubs.rsc.org/en/content/articlelanding/2020/qo/d0qo01321h/unauth#!divAbstract

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