李明，教授，博士，材料物理系

中南大学材料科学与工程学院教授，国家“四青”人才， 博士生导师

课题组主页： https://ming-group.com/

Group Website: https://ming-group.com/

 https://orcid.org/0000-0002-2289-0222

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博士毕业于美国西弗吉尼亚大学

硕士毕业于浙江大学材料科学与工程学院

本科毕业于大连理工大学精细化工系

先后在美国圣母大学、麻省理工学院和约翰霍普金斯大学从事博士后研究工作。

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研究方向：

主要从事新型生物医用材料、生物传感器和体外检测等方面的基础研究和应用研究，在新型表面等离激元材料研制及表面等离激元学、用于体外检测的生物传感技术开发、以及高分辨共聚焦拉曼显微学等方面做了长期系统性研究。曾获得国家优秀自费留学生奖（2011）和美国激光医学和手术协会fellowship（2015）等多项奖。近年来，课题组在Nature Communications、Advanced Materials、Angewandte Chemie International Edition、ACS Nano、Advanced Functional Materials、Nano Letters、Coordination Chemistry Reviews、Chemical Engineering Journal、Small、Chemistry of Materials、Analytical Chemistry、Biosensors and Bioelectronics、ACS Sensors、Inorganic Chemistry和Journal of Materials Chemistry B/C等主流学术期刊发表学术论文70余篇，SCI引用次数10000余次。

主要从事以下几个方面的研究：

1、新型生物医用材料；

2、生物传感器和医学体外检测，侧重于癌症等重大疾病的早期诊断检测；

3、可穿戴式生物传感器和医疗器械。

联系方式：liming0823 at csu.edu.cn 或liming0823 at gmail.com(at 用 @ 替代）。

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课程讲授

1.《生物材料》每年秋冬学期，64学时4学分，材料科学与工程学院材料国际专业和材料学院卓越班

2. 《生物医用材料及生物传感》每年秋冬学期，72学时，湘雅附二临床医学（五年制）卓越医生班

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代表性论文

（https://scholar.google.com/citations?hl=en&user=m5IrnO8AAAAJ&view_op=list_works&sortby=pubdate）

48. Renting Jiang, Linhu Li, Ming Li*

      Biomimetic Construction of Degradable DNAzyme-Loaded Nanocapsules for Self-Sufficient Gene Therapy

      of Pulmonary Metastatic Breast Cancer

      ACS Nano 2023, DOI: 10.1021/acsnano.3c09581

47. Renting Jiang#, Jianqin Li#, Linhu Li, Yaxuan Lu, Huiming Zhang, Ming Li*

      Engineering Near-Infrared Plasmonic Spiky Gold Nanostructures for Highly Efficient Surface-Enhanced Raman 

      Spectroscopy-Guided Cancer Hyperthermia Therapy        

       Advanced Functional Materials 2023, DOI: 10.1002/adfm.202307631

46.  Yangcenzi Xie, MingyangChen, Xinyu Liu, Xiaoming Su, Ming Li*

       Artificial Intelligence-Assisted Label-Free Spectroscopic Quantification of Global DNA Cytosine Methylation in

       a Miniature Plasmonic Pickering Emulsion
            Advanced Functional Materials 2023, DOI: 10.1002/adfm.202307091.

45. Xiaoming Su, Yangcenzi Xie, Xinyu Liu, Mingyang Chen, Chao Zheng, Hong Zhong*, Ming Li*

       Absolute Quantification of Serum Exosomes in Patients with an SERS-Lateral Flow Strip Biosensor for Noninvasive

       Clinical Cancer Diagnosis
             ACS Applied Materials & Interfaces 2023, 15(31), 37130–37142.

44. Haitao Wang, Huiming Zhang, Beibei Shan, Renata Solarska, Ming Li*

       Symmetry-Breaking Effects of Near-Infrared II Thermoplasmonics of Gold–Silica–Cuprous Selenide Hybrid

       Nanoshells

       The Journal of Physical Chemistry C  2023, 127(22), 10757–10765.

43.  Huiming Zhang, Ting Zhu, Ming Li*

       Quantitative Analysis of the Shape Effect of Thermoplasmonics in Gold Nanostructures
          The Journal of Physical Chemistry Letters 2023, 14 (16), 3853-3860.

42.  Bin Meng, Yong Xie, Le Chen, Haitao Wang, Ming Li,* Zhuxin Dong*

       Apex-Confined Plasmonic Tip for High Resolution Tip-Enhanced Raman Spectroscopic Imaging of

       Carbon Nanotubes

      ACS Applied Materials & Interfaces, 2023, 15(13), 16984–16990.

41. Xiaoming Su, Xinyu Liu, Yangcenzi Xie, Mingyang Chen, Chao Zheng, Hong Zhong,* Ming Li*

      Integrated SERS-Vertical Flow Biosensor Enabling Multiplexed Quantitative Profiling of Serological Exosomal

     Proteins in Patients for Accurate Breast Cancer Subtyping

     ACS Nano 2023, 17(4), 4077–4088

40. Xiaoming Su, Xinyu Liu, Yangcenzi Xie, Mingyang Chen, Hong Zhong,* Ming Li*

     Quantitative Label-Free SERS Detection of Trace Fentanyl in Biofluids with a Freestanding Hydrophobic Plasmonic

     Paper Biosensors

    Analytical Chemistry 2023, 95(7), 3821–3829

39. Mingyang Chen, Renata Solarska, Ming Li*

      Additional Important Considerations in Surface-Enhanced Raman Scattering Enhancement Factor Measurements

      Journal of Physical Chemistry C 2023, 127(5), 2728–2734 

38. Yangcenzi Xie, Xiaoming Su, Yu Wen, Chao Zheng,* and Ming Li*

     Artificial intelligent label-free SERS profiling of serum exosomes for breast cancer diagnosis

     and postoperative assessment

     Nano Letters, 2022, 22(19), 7910–7918.

37. Linhu Li, Renting Jiang, Beibei Shan, Yaxuan Lu, Chao Zheng, and Ming Li*

     Near-infrared II plasmonic porous cubic nanoshells for in vivo noninvasive SERS visualization

     of sub-millimeter microtumors

    Nature Communications, 2022, 13, 5249.

36. Yangcenzi Xie, Yu Wen, Xiaoming Su, Chao Zheng, and Ming Li*

     Label-free plasmon-enhanced spectroscopic HER2 detection for dynamic therapeutic surveillance

     of breast cancer

    Analytical Chemistry, 2022, 94(37), 12762–12771.

35. Guangzhi Zhou, Ming Li*

     Biodegradable copper telluride nanosheets for redox-homeostasis breaking-assisted chemodynamic

    cancer therapy boosted by mild-photothermal effect

    Chemical Engineering Journal, 2022, 450, 138348

34. Huyun Liu, Renting Jiang, Yaxuan Lu, Beibei Shan, Yu Wen, and Ming Li*

     Biodegradable Amorphous Copper Iron Tellurite Promoting the Utilization of Fenton-like Ions 

     for Efficient Synergistic Cancer Theranostics

     ACS Applied Materials & Interfaces, 2022, 14 (25), 28537-28547

33. Beibei Shan, Yaxuan Lu, Chao Zheng, Ming Li*

      Structural symmetry effects in plasmonic metal-semiconductor hybrid heterostructures for multimodal

      cancer phototheranostics

     Chemical Engineering Journal, 2022, 444, 136707.

32. Guangzhi Zhou, Ming Li*

      Near‐infrared II plasmonic tri‐enzyme integrated metal‐organic frameworks with high‐efficiency enzyme 

      cascades for synergistic tri‐modal oncotherapy

     Advanced Materials, 2022, 34(24), 2200871.

31. Beibei Shan, Huyun Liu, Linhu Li, Yaxuan Lu, Ming Li*

      Near-infrared II plasmonic phototheranostics with glutathione depletion for multimodal imaging-guided

      hypoxia-tolerant chemodynamic-photocatalytic-photothermal cancer therapy triggered by a single laser

       Small, 2022, 18(4), 2105638. 

30. Yu Wen, Junjiao Hu, Jun Liu, Ming Li*

       Degradable carrier-free metal−phenolic network theranostic agent with targeted mitochondrial damage for

       efficient cancer theranostics

        Chemistry of Materials,  2021, 33(17), 7089-7099. 

29. Mengling Liao, Beibei Shan, Ming Li*

      Role of trap states in excitation wavelength-dependent photoluminescence of strongly quantum-confined

      all-inorganic CsPbBr₃ perovskites with varying dimensionalities

     The Journal of Physical Chemistry C, 2021, DOI: 10.1021/acs.jpcc.1c06394.

28. Jiayi Tan, Yu Wen, Ming Li*

      Emerging biosensing platforms for quantitative detection of exosomes as diagnostic biomarkers

      Coordination Chemistry Reviews, 2021, 446, 214111

27. Xi Wang, Changxu Liu, Congcong Gao, Kaili Yao, Seyed Shayan Mousavi Masouleh, Rodrigo Berté, Haoran Ren,

      Leonardo de S Menezes, Emiliano Cortés, Isobel C Bicket, Haiyu Wang, Ning Li, Zhenglong Zhang, Ming Li, 

     Wei Xie, Yifu Yu, Yurui Fang, Shunping Zhang, Hongxing Xu, Alberto Vomiero, Yongchang Liu, Gianluigi A Botton,

     Stefan A Maier, Hongyan Liang

     Self-Constructed Multiple Plasmonic Hotspots on an Individual Fractal to Amplify Broadband Hot Electron

     Generation

     ACS Nano 2021, 15(6), 10553–10564.

26. Jianqin Li, Hangduo Lin, Xiaolin Zhang, Ming Li*

       Seed shape-controlled, facet-selective growth of superspiky gold nanocrystals for biosensing applications.

      Journal of Materials Chemistry C, 2021, 9, 8694-8704.

25. Beibei Shan, Linhu Li, Yawen Zhao, Haitao Wang, Ming Li*

      Near-infrared II plasmonic Au@Au-Ag dot-in-cubic nanoframes for in vivo surface-enhanced Raman

      spectroscopic detection and photoacoustic imaging.

     Advanced Functional Materials, 2021, 31(29), 2103186.

24. Haitao Wang, Ming Li*

     Near-Infrared II thermoplasmonics of cuprous selenide multilayer nanoshells: the role of the plasmonic core. 

    The Journal of Physical Chemistry Letters, 2021, 12, 4928-4935.

23. Yu Wen, Vinh X. Truong, Ming Li*

     Real-time intraoperative surface-enhanced Raman spectroscopy-guided thermosurgical eradication of

     residual microtumors in orthotopic breast cancer

     Nano Letters, 2021, 21(7), 3066–3074.

22. Caiju Chen, Huyun Liu, Haitao Wang, Yawen Zhao, Ming Li*

     A scalable broadband plasmonic cuprous telluride nanowire-based hybrid photothermal membrane for

     efficient solar vapor generation

     Nano Energy, 2021, 84, 105868.

21. Beibei Shan, Haitao Wang, Linhu Li, Guangzhi Zhou, Yu Wen, Mingyang Chen, Ming Li*

    Rationally designed dual-plasmonic gold nanorod@cuprous selenide hybrid heterostructures by

    regioselective overgrowth for in vivo photothermal tumor ablation in the second near-infrared biowindow

   Theranostics, 2020, 10(25), 11656-11672.

20. Ming Li, Scott K. Cushing, Guangwen Zhou, Nianqiang Wu

   Molecular hot spots in surface-enhanced Raman scattering

   Nanoscale, 2020, 12, 22036–22041.

19. Ming Li*, Hangduo Lin, Santosh Kumar Paidi, Nicolas Mesyngier, Sarah P Preheim, Ishan Barman

   A fluorescent and surface-enhanced Raman spectroscopic dual-modal aptasensor for sensitive detection

    of cyanotoxins

   ACS Sensors, 2020, 5(5), 1419-1426.

18. Ming Li*, Andrew P. Dove, Vinh Xuan Truong

  Additive-Free Green Light-Induced Ligation Using BODIPY Triggers

  Angewandte Chemie International Edition, 2020, 59, 2284 –2288.

17. Beibei Shan, Yawen Zhao, Yiwen Li, Haitao Wang, Rui Chen, Ming Li*

  High-Quality Dual-Plasmonic Au@Cu_2-xSe Nanocrescents with Precise Cu_2-xSe Domain Size Control and Tunable

  Optical Properties in the Second Near-Infrared Biowindow

  Chemistry of Materials, 2019, 31, 9875?9886.

16. Xiang Pan, Linhu Li, Hangduo Lin, Jiayi Tan, Haitao Wang, Mengling Liao, Caiju Chen, Beibei Shan,

    Yingfan Chen, Ming Li*

   A graphene oxide-gold nanostar hybrid based-paper biosensor for label-free SERS detection of serum

   bilirubin for diagnosis of jaundice

   Biosensors and Bioelectronics, 2019, 145, 111713.

15. Ming Li,* Santosh Kumar Paidi, Eric Sakowski, Sarah Preheim and Ishan Barman*

   Ultrasensitive Detection of Hepatotoxic Microcystin Production from Cyanobacteria Using Surface-Enhanced

    Raman Scattering Immunosensor

   ACS Sensors, 2019, 4, 1203-1210.

14. Mengling Liao, Beibei Shan and Ming Li*

     In Situ Raman Spectroscopic Studies of Thermal Stability of All-Inorganic Cesium Lead Halide (CsPbX3, X = Cl, Br, I)

      Perovskite Nanocrystals

     The Journal of Physical Chemistry Letters, 2019, 10 (6), 1217–1225.

13. Beibei Shan, Yuhan Pu, Yingfan Chen, Mengling Liao and Ming Li*

    Novel SERS Labels: Rational Design, Functional Integration and Biomedical Applications

    Coordination Chemistry Reviews, 2018, 371, 11-37.

12. Qianru Jin# (co-first author), Ming Li# (co-first author), Beril Polat, Santosh K. Paidi, Aimee Dai, Amy Zhang,

   Jayson V. Pagaduan, Ishan Barman, David H. Gracias

    Mechanical Trap Surface‐Enhanced Raman Spectroscopy for Three‐Dimensional Surface Molecular Imaging of

    Single Live Cells

  Angewandte Chemie International Edition, 2017, 56, 3822-3826.

11. Ming Li*, Sangeeta Ray Banerjee, Chao Zheng, Martin G. Pomper, and Ishan Barman

   Ultrahigh Affinity Raman Probe for Targeted Live Cell Imaging of Prostate Cancer

   Chemical Science, 2016, 7, 6779-6785.

10. Ming Li*, Jeon Woong Kang, Saraswati Sukumar, Ramachandra R. Dasari, and Ishan Barman

    Multiplexed Detection of Serological Cancer Markers with Plasmon-Enhanced Raman Spectro-immunoassay

    Chemical Science, 2015, 6, 3906-3914.

9. Ming Li, Jeon Woong Kang, Ramachandra Rao Dasari, and Ishan Barman

   Shedding Light on the Extinction-Enhancement Duality in Gold Nanostar-Enhanced Raman Spectroscopy

   Angewandte Chemie International Edition, 2014, 53, 14115-14119.

8. Scott K. Cushing# (co-first author), Ming Li# (co-first author), Fuqiang Huang, and Nianqiang Wu

   Origin of Strong Excitation Wavelength Dependent Fluorescence of Graphene Oxide

   ACS Nano, 2014, 8, 1002-1013.

7. Ming Li, Scott K. Cushing, Jianming Zhang, Savan Suri, Rebecca Evans, William P. Petros, Laura F. Gibson,

   Dongling Ma, Yuxin Liu, and Nianqiang Wu

  Three-Dimensional Hierarchical Plasmonic Nano-architecture Enhanced Surface-Enhanced Raman Scattering

   Immuno-Sensor for Cancer Biomarker Detection in    Blood Plasma

  ACS Nano, 2013, 7, 4967-4976.

6. Ming Li, Scott K. Cushing, Hongyan Liang, Savan Suri, Dongling Ma, and Nianqiang Wu

   Plasmonic Silver Nanorice Antenna on Gold Triangle Nano-array for Surface-Enhanced Raman Scattering

   Detection of Hepatitis B Virus DNA

   Analytical Chemistry, 2013, 85, 2072-2078.

5. Ming Li, Xuejiao Zhou, Shouwu Guo, and Nianqiang Wu

  Detection of Lead (II) with a “Turn-On” Fluorescent Sensor Based on Energy Transfer from CdSe/ZnS

  Quantum Dots to Graphene Oxide

  Biosensors & Bioelectronics, 2013, 43, 69-74.

4. Ming Li, Xuejiao Zhou, Weiqiang Ding, Shouwu Guo, and Nianqiang Wu

  Fluorescent Aptamer-Functionalized Graphene Oxide for Label-Free Detection of Mercury (II)

  Biosensors & Bioelectronics, 2013, 41, 889-893.

3. Ming Li, Xuejiao Zhou, Shouwu Guo, and Nianqiang Wu

  Fingerprinting Photoluminescence of Functional Groups in Graphene Oxide

  Journal of Materials Chemistry, 2012, 22, 23374-23379.

2. Ming Li, Qiaoyi Wang, Xiaodong Shi, Lawrence A. Hornak, and Nianqiang Wu

   Detection of Mercury (II) by Quantum dot-DNA-Gold Nanoparticle Ensemble Based Nanosensor via Nanometal

   Surface Energy Transfer

   Analytical Chemistry, 2011, 83, 7061-7065.

1. Ming Li, Scott K. Cushing, Qiaoyi Wang, Xiaodong Shi, Lawrence A. Hornak, Zhanglian Hong, and Nianqiang Wu

   Size-dependent Energy Transfer between CdSe/ZnS Quantum Dots and Gold Nanoparticle

   The Journal of Physical Chemistry Letters, 2011, 2, 2125-2129.