涂超峰，遗传学博士，副教授，博士生导师，中南大学升华学者，湖南省优青，湖湘青年英才支持计划获得者，中信湘雅生殖与遗传专科医院男科学部副主任。长期从事男性不育的基础与临床转化研究，在特发性男性不育新基因的鉴定及其致病机制研究领域取得了多项原创性研究成果，以第一/通讯作者（含并列）在《Cell Discovery》， 《Nature Communications》，《Science Bulletin》，《Advanced Science》，《American Journal of Human Genetics》（3篇），《Autophagy》，《Human Reproduction Update》等杂志发表论文30余篇，其中9篇IF>10，申请发明专利10项，授权2项；先后主持国家自然科学基金面上及青年项目、中国博士后科学基金面上项目、湖南省自然科学基金等项目。曾获中国妇幼健康科技成果奖二等奖（排名第三），中南大学优秀教师奖等荣誉。
代表性论文
1. Tu C#, Wen J#, Wang W#, Zhu Q#, Chen Y, Cheng J, Li Z, Meng L, Li Y, He W, Tan C, Xie C, Fu SM, Du J, Lu G, Lin GJ*, Gou LTJ*, Tan YQJ*. Loss-of-function variants in human C12orf40 cause male infertility by blocking meiotic progression. Cell Discov. 2023 Aug 22;9(1):87. (Q1, IF:33.8)
2. Tu C#, Li HY, Liu XY, Wang Y, Li W, Meng L, Wang W, Li Y, Li D, Du J, Lu G, Lin G, Tan YQ*. TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation. Autophagy. 2021.3:1-17. (Q1, IF:16.016)
3. Tu C#, Cong JS#, Zhang QJ#, He XJ#, Zheng R,Yang X, Gao Y, Wu H, Lv M, Gu Y, Lu S, Liu C, Tian S, Meng L, Wang W, Tan C, Nie H, Li D, Zhang H, Gong F, Hu L, Lu G, Xu W, Lin G, Zhang F, Cao Y*, Tan YQ*. Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. Am J Hum Genet. 2021;108(8):1466-1477. (Q1, IF: 11.025)
4. Tan C, Hu T, Meng L, Lam KK, Zhang Q, Xu X, Yuan S, Wang Y, Huang Z, Zhou K, Li Y, Xie C, Luo C, Chen Z, Zhang H, Hu J, Wang W, Lu G, Xu W, Zhang Q, Zhang F, Chung JPW, Choy KW, Hu L, Du J, He W*, Tu C*, Lin G*, Dong Z*, Tan YQ*. Genomic landscape of idiopathic male infertility and the pregnancy outcomes following assisted reproductive technology. Sci Bull (Beijing). 2026 Aug 2:S2095-9273(26)00869-8. (Q1=20.70)
5. Xie C, Yi S, Lin X, Zhang S, Wang W, Yuan S, Meng L, Li Y, Tan C, Wei C, Yu Y, Liang Y, Zhang H, Hu L, Lu G, He W, Zhang Q, Du J, Lin G, Tu C*, Tan YQ*. The KIF6-RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly. Adv Sci . 2026 Jun 25:e76263. (Q1=14.1)
6. Wu T#, Tu C#, Feng Y#, Qu W#, Chen J#, Wu H#, Gao W, Xu B, Yu X, Bao M, Xu J, Zhou N, Hu H, Jiang B, Xie Q, Meng L, Tan C, Lin G, Shen C, Chen X, Guo Y, Zhou T, Liang Y, Hua R, Cao Y, Liu M, Yu J*, Huang X*, Tan YQ*, Zheng B*. A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility. Nat Commun. 2026 Feb 24;17(1):3100. (Q1=14.7)
7. Liu CY#, Tu C#, Wang LB#, Wu H#, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ*, Zhang F*. Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility. Am J Hum Genet. 2021;108(2):309-323. (Q1, IF: 11.025)
8. Liu C#, Si W#, Tu C#, Tian S#, He X#, Wang S#, Yang X#, Yao C#, Li C, Kherraf ZE, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, Liu Q, Tang S, Wang J, Saiyin H, Zhao L, Yang L, Meng L, Chen B, Tang D, Zhou Y, Wu H, Lv M, Tan C, Lin G, Kong Q, Shi H, Su Z, Li Z, Yao YG, Jin L, Zheng P, Ray PF, Tan YQ*, Cao Y*, Zhang F*. Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models. Am J Hum Genet. 2023; 110(3): 516-530. (Q1, IF: 11.025)
9. Liu C#, Tu C#, Li P#, Wu H#, Wan F#, Lu Y#, Tang S, Li X, Li K, Wang J, Gao Y, Geng X, Meng L, Zhou D, Zhou Y, Zhou Z, Guo H, Cao Y, Jin L, Li Z, He X*, Tan YQ*, Sun Q*, Zhang F*. Deficiency of primate-specific TFDP3 causes male infertility with oligoasthenoteratozoospermia in humans and cynomolgus monkeys. Sci China Life Sci. 2026 May;69(5):1594-1603. (Q1, IF:9.5)
10. Zhou Y#, Tu C#, Coutton C#, Tang J#, Tian S#, Tang S, Martinez G, Zhou D, Tebbakh C, Wang J, Zouari R, Zhou X, Ben Mustapha SF, Wang X, Wu B, Geng X, Liu S, Jin L, Shi H, Tan YQ, Ray PF, Wang L, Yang X*, Zhang F*, Liu C*. Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice. Sci China Life Sci. 2025 Mar;68(3):777-792. (Q1, IF:9.5)
11. Tu C, Meng L, Nie H, Yuan S, Wang W, Du J, Lu G, Lin G, Tan YQ*. A homozygous RPL10L missense mutation associated with male factor infertility and severe oligozoospermia. Fertil Steril. 2020;113(3):561-568. (Q1, IF: 7.329)
12. Wang W#, Su L#, Meng L, He J, Tan C, Yi D, Cheng D, Zhang H, Lu G, Du J, Lin G, Zhang Q*, Tu C*, Tan YQ*. Biallelic variants in KCTD19 associated with male factor infertility and oligoasthenoteratozoospermia. Hum Reprod. 2023 Jul 5;38(7):1399-1411.(Q1, IF: 6.1)
学术任职
1、中国优生科学协会医学遗传学专业委员会常务委员
2、中国性学会生殖检验分会常务委员
3、中国非公立医疗机构协会男性生殖与性医学专业委员会常务委员
4、湖南省医学会男科学专业委员会第三届男性不育与生殖学组委员