The association of adiponectin allele 45T/G and -11377C/G polymorphisms with Type 2 diabetes and rosiglitazone response in Chinese patients
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所属单位：
Department of Pharmacy, Fujian Provincal Hospital
教研室：
Department of Pharmacy,Fujian Provincal Hospital
发表刊物：
british journal of clinical pharmacology
刊物所在地：
britsh
项目来源：
National Natural Science Foundation of China
关键字：
C-11377G polymorphism, T45G polymorphism, adiponectin, diplotype, rosiglitazone efficacy, Type 2 dia
摘要：
Abstract
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT:
Rosiglitazone is able to increase serum adiponectin levels significantly in Type 2 diabetic patients. :The role of genetic factors that determine the marked interindividual variability in glucose-lowering efficacy of rosiglitazone in Chinese patients is not known. The current study was designed to evaluate the impact of the adiponectin common allele 45T/G and -11377C/G polymorphisms on the response to rosiglitazone monotherapy in Chinese patients with Type 2 diabetes (T2D).
WHAT THIS STUDY ADDS:
The genetic polymorphisms of adiponectin allele
合写作者：
Liu ZQ*, Wu J, Zhou HH, Guo ZW, Liu YZ, Liu HL, Yin JY, Gong ZC#, Sun H#*
论文类型：
基础研究
论文编号：
DOI:10.1111/j.1365-2125.2008.03145.x
学科门类：
临床医学
文献类型：
J
卷号：
65
期号：
6
页面范围：
917-926
ISSN号：
1365-2125
是否译文：
否
附件：
学位：博士学位
职称：教授
学科：临床医学
所在单位：中南大学湘雅医院