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所属单位:
Central South University
教研室:
Institute of Clinical Pharmacology
发表刊物:
Eur J Clin Pharmacol.
刊物所在地:
Europe
项目来源:
he National “created a major new drugs”-Science and Technology Major Project (No. 2009ZX09304)
关键字:
SLC30A8 rs13266634 . SLC30A8 rs16889462 . Genetic polymorphisms . Type 2 diabetes mellitus . Repagli
摘要:
Abstract
OBJECTIVE:
Genome-wide association studies (GWASs) identified that SLC30A8 genetic polymorphism was a risk of type 2 diabetes mellitus (T2DM) in several populations. This study aimed to investigate whether the SLC30A8 rs13266634 and rs16889462 polymorphisms were associated with T2DM susceptibility and repaglinide therapeutic efficacy in Chinese T2DM patients.
METHODS:
We conducted a case-control study of 443 T2DM patients and 229 healthy volunteers to identify SLC30A8 rs13266634 and rs16889462 genotypes by polymerase chain reaction-restriction fragment length polymorphism ……(
合写作者:
Liu ZQ., Zhou HH, Gong ZC, Yu M, Deng CS, Chen X, Wu J, Dai XP, Yin JY, Huang Q1
论文类型:
基础研究
论文编号:
doi: 10.1007/s00228-010-0882-6.
学科门类:
临床医学
文献类型:
J
卷号:
66
期号:
12
页面范围:
1207–1215
ISSN号:
doi: 10.1007/s00228-010-0882-6.
是否译文:
否
附件: