Hui Guo, PhD, is a Professor (Research Track) and PhD supervisor at Central South University.

He received his Bachelor of Science degree in Biological Sciences from Central South University in June 2008. In the same year, he was admitted, through the recommendation-based admission scheme, to the master’s program in Genetics at the State Key Laboratory of Medical Genetics. In September 2010, he transferred to the doctoral program ahead of schedule. From October 2011 to October 2012, supported by the China Scholarship Council’s Joint PhD Training Program, he undertook joint doctoral training and research in the laboratory of Daniel R. Weinberger, a member of the US National Academy of Medicine, at the National Institute of Mental Health (NIMH), National Institutes of Health (NIH), USA. He received his PhD in Genetics from the State Key Laboratory of Medical Genetics in December 2013.

In 2014, he joined the School of Life Sciences at Central South University as a Lecturer and received support through the university’s Shenghua Lieying Talent Program. He was promoted to Associate Research Professor through an exceptional promotion in 2015. From 2017 to 2019, he conducted collaborative research as a visiting scholar and received postdoctoral training in the laboratory of Professor Evan E. Eichler, a member of the US National Academy of Sciences, at the University of Washington School of Medicine. He was promoted to Professor (Research Track) at Central South University in 2020, appointed Head of the Department of Genetics in 2022, and appointed Associate Dean of the School of Life Sciences in 2023.

Dr. Guo’s laboratory combines medical genetics and bioinformatics with neurobiology, cell biology, biochemistry, molecular biology, and model-organism approaches to investigate genetic regulatory mechanisms and precision diagnosis and treatment for autism and other neurodevelopmental disorders. His work as a corresponding author has been published in the Journal of Clinical Investigation (2025, 2022), Molecular Psychiatry (2026a, 2026b, 2024), Science Advances (2022, 2019), Proceedings of the National Academy of Sciences (2026), and the American Journal of Human Genetics (2026, 2020). He has led five projects funded by the National Natural Science Foundation of China, including an Excellent Young Scientists Fund project, and has undertaken projects under the major national program on Brain Science and Brain-Inspired Research.

He was selected for the inaugural Young Elite Scientists Sponsorship Program of the China Association for Science and Technology, the Hunan Leading Talents in Science and Technology Innovation Program, the Hunan Distinguished Young Scholars Program, the Hunan Furong Young Scholars Program, and the Huxiang Young Talents Program. His awards include the First Prize in Natural Sciences of the National Maternal and Child Health Science and Technology Award, an Outstanding Achievement Award recognizing China’s emerging science and technology figures, and the Second Prize of the Hunan Provincial Teaching Achievement Award.

He serves as a Council Member of the Genetics Society of China, Secretary-General of the Branch of Childhood Cognition and Brain Dysfunction of the Chinese Neuroscience Society, a member of the Youth Committee of the Genetics Society of China, and a member of its Behavioral Genetics Branch. He is an Associate Editor of Cellular and Molecular Life Sciences and has reviewed manuscripts for Cell Research, the American Journal of Human Genetics, Molecular Psychiatry, Genome Medicine, Cell Reports, EMBO Molecular Medicine, and Genetics in Medicine.