Chen Q., Le X., Wen Q., Cao S., Guo Y., Weng X., Zhang L., Wei J., Zou M., Hu L., Li Q., Liu S., Chen Z. Discovery of Cdc20/Hsp90 Dual-Target Inhibitors with Potent Antitumor Activity for Therapy of Acquired Resistant Melanoma. J Med Chem, 2025, 68(21): 22428-22454.
Hits:
|
Pre One:Cao M., Guo Y., Tan W., Feng C., Chen Q., Yao M., Xu J., Chen Z., Li Q. Novel sodium-hydrogen exchanger 1 inhibitors with diphenyl ketone scaffold: Design, Synthesis, mechanism and evaluation in mice model of heart failure. Eur J Med Chem, 2025, 291: 117585.
Next One:Guo Y., Cao M., Li Z., Zhou H., Chen Z., Li Q. Discovery of a novel 2,4-thiazolidinedione derivative as dual inhibitor of beta-catenin/TCF4 interaction and tubulin polymerization in colon cancer cells. Arch Pharm (Weinheim), 2025, 358(3): e2400796.
