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          谭跃球，中南大学研究员，二级教授，医学遗传学博士，博士研究生导师。现任中信湘雅生殖与遗传专科医院遗传中心主任。并担任《中华医学遗传学杂志》编委，中国优生优育协会理事，中华医学会医学细胞生物学分会委员，中国遗传学会遗传咨询分会委员会委员，中国遗传学会国际交流委员会委员，湖南省医学会生殖医学分会和湖南省医学遗传学分会委员等学术职务。
          1991年获湖南师范大学生物学学士学位，1997年和2002年先后获湖南医科大学医学遗传学遗传学硕士和中南大学遗传学博士学位。国家重点研发计划课题/国家重点基础研究计划（973计划）课题负责人或骨干 4 项，主持国家自然科学基金4项及省部级课题 7 项。获国家科技进步二等奖 1 项，获教育部科学技术进步奖（推广奖）一等奖 1 项。

          发表论文 199 篇，其中以一作/通讯作者 (含并列) 在包括《New England Journal of Medicine》、《Cell Discovery》、《American Journal of Human Genetics》、《Autophagy》、《Genetics in Medicine》、《Human Reproduction Update》、《Human Reproduction》、《Fertility and Sterility》、《Journal of Medical Genetics》等SCI收录期刊发表论文 110 余篇。2006年获“湖南省青年骨干教师”，2013年获“湖南省医学学科骨干人才”，2019年获“湖南省医学（医学遗传学）学科带头人”。

         近 5年 代表性论文（#为通讯作者）：

1.             Wang X, Tan YQ^#, Liu MF#. Defective piRNA Processing and Azoospermia. N Engl J Med. 2022 Apr 28;386(17):1674-1675. doi: 10.1056/NEJMc2116008. PMID: 35476664.

2.             Li L, Tan YQ, Lu LY. Defective piRNA Processing and Azoospermia. N Engl J Med. 2022 Apr 28;386(17):1675-1676. doi: 10.1056/NEJMc2116008. PMID: 35476666.

3.             Tu C, Wen J, Wang W, Zhu Q, Chen Y, Cheng J, Li Z, Meng L, Li Y, He W, Tan C, Xie C, Fu S, Du J, Lu G, Lin G, Gou LT#, Tan YQ^#. Loss-of-function variants in human C12orf40 cause male infertility by blocking meiotic progression. Cell Discovery. 2023. DOI : 10.1038/s41421-023-00580-w.

4.             Zhou S, Yuan S, Zhang J, Meng L, Zhang X, Liu S, Lu G, Lin G, Liu M^#, Tan YQ^#. DRC3 is an assembly adapter of the nexin-dynein regulatory complex functional components during spermatogenesis in humans and mice. Signal Transduct Target Ther. 2023 Jan 10;8(1):26. doi: 10.1038/s41392-022-01293-4.  PMID: 36627292.

5.             Lu S, Gu Y, Wu Y, Yang S, Li C, Meng L, Yuan W, Jiang T, Zhang X, Li Y, Wang C, Liu M, Ye L, Guo X, Shen H, Yang X, Tan Y^#, Hu Z^#. Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly. Cell Discovery. 2021 Nov 16;7(1):110.  

6.             Tu C, Cong J, Zhang Q, He X, Zheng R, Yang X, Gao Y, Wu H, Lv M, Gu Y, Lu S, Liu C, Tian S, Meng L, Wang W, Tan C, Nie H, Li D, Zhang H, Gong F, Hu L, Lu G, Xu W, Lin G, Zhang F, Cao Y^#, Tan YQ^#. Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. Am J Hum Genet. 2021 Aug 5;108(8):1466-1477.

7.             Tu C, Li H, Liu X, Wang Y, Li W, Meng L, Wang W, Li Y, Li D, Du J, Lu G, Lin G#, Tan YQ^#. TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation. Autophagy. 2021 Nov; 17(11): 3848-3864.

8.             Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ#, Zhang F#. Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility. Am J Hum Genet. 2021 Feb 4;108(2):309-323.

9.             Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G#, Tan YQ#. Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice. Am J Hum Genet. 2022 Jan 6;109(1):157-171.

10.          Xie C, Wang W, Tu C, Meng L, Lu G, Lin G, Lu LY, Tan YQ#. Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia. Hum Reprod Update. 2022 May 25:dmac024. doi: 10.1093/humupd/dmac024. Epub ahead of print. PMID: 35613017.

11.          Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao C, Li C, Kherraf ZE, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, Liu Q, Tang S, Wang J, Saiyin H, Zhao L, Yang L, Meng L, Chen B, Tang D, Zhou Y, Wu H, Lv M, Tan C, Lin G, Kong Q, Shi H, Su Z, Li Z, Yao YG, Jin L, Zheng P, Ray PF, Tan YQ*, Cao Y*, Zhang F*. Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models. Am J Hum Genet. 2023 Mar 2;110(3):516-530.( *contributed equally)

12.          Tan YQ, Tu CF, Meng LL, Yuan SM, Sjaarda C, Luo AX, Du J, Li W, Gong F, Zhong CG, Deng HX, Lu GX, Liang P, Lin G. Loss-of-function mutations TDRD7 lead to a rare novel syndrome combining congenital cataract and non-obstructive azoospermia in humans. Genet Med. 2019;21(5):1209-1217.

13.          Hu T, Meng L, Tan C, Luo C, He WB, Tu C, Zhang H, Du J, Nie H, Lu GX, Lin G, Tan YQ^#. Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermia. J Med Genet. 2023 Feb;60(2):144-153.

14.          Wang W, Su L, Meng L, He J, Tan C, Yi D, Cheng D, Zhang H, Lu G, Du J, Lin G, Zhang Q#, Tu C#, Tan YQ^#. Biallelic variants in KCTD19 associated with male factor infertility and oligoasthenoteratozoospermia. Hum Reprod. 2023 May 16:dead095. doi: 10.1093/humrep/dead095. Epub ahead of print. PMID: 37192818.

15.    Tu C, Meng L, Nie H, Yuan S, Wang W, Du J, Lu G, Lin G, Tan YQ^#. A homozygous RPL10L missense mutation associated with male factor infertility and severe oligozoospermia. Fertil Steril. 2020 Mar;113(3):561-568.

16.          He WB, Tan C, Zhang YX, Meng LL, Gong F, Lu GX, Lin G, Du J, Tan YQ^#. Homozygous variants in SYCP2L cause premature ovarian insufficiency. J Med Genet. 2021 Mar;58(3):168-172.

17.          Wang W, Tian S, Nie H, Tu C, Liu C, Li Y, Li D, Yang X, Meng L, Hu T, Zhang Q, Du J, Fan L, Lu G, Lin G, Zhang F^#, Tan YQ^#. CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis. Hum Mol Genet. 2021 Nov 16;30(23):2240-2254.