Improved biological compatibility of carbon materials via aqua regia and CaCl2 treatments
发布时间：2024-07-05
点击次数：
DOI码：10.1016/j.matchemphys.2023.127359
发表刊物：Materials Chemistry and Physics
关键字：Single-phase carbon Hydroxyapatite Bioactivity Surface modiffcations Cell ultrastructure
摘要：In order to improve the bioactivity of three single-phase carbon materials (resin, pyrocarbon and graphite), chemical modiffcation with aqua regia and CaCl2 solution was used to modify their original surfaces. The bioactivity of materials before and after modiffcation was evaluated by in vitro apatite formation in simulated body ffuids (SBF). The results showed that –COOH and Ca2+ were introduced on the sample surface by the chemical modiffcation. The treated resin demonstrated the strongest ability to form a uniform and dense HAP coating after soaking in SBF for its largest speciffc surface area and the highest content of -COO- . The bone-like apatite coating demonstrated remarkably enhanced in vitro biocompatibility as indicated in the mouse ffbroblast (L929) direct contact and ultrastructure observation. The transformation process of hydroxyapatite morphology in functional carbon materials, and the hydroxyapatite formation mechanism were systematically analyzed.
论文类型：文章
学科门类：工学
一级学科：材料科学与工程
文献类型：J
卷号：296
页面范围：127359
是否译文：否
发表时间：2023-01-06
收录刊物：SCI
附件：
Improved biological compatibility of carbon materials via aqua regia and CaCl2 treatments-陈红梅.pdf