Language : English
Xiaoqing Chen
  • Personal Information

    Professor


    Supervisor of Doctorate Candidates


    Supervisor of Master's Candidates

    School/Department:Chemistry and Chemical Engineering

    Education Level:PhD Graduate

    Business Address:湖南省长沙市潇湘中路中南大学新校区化学化工学院345

    Sex:Female

    Contact Information:邮箱:xqchen@csu.edu.cn 电话:13974833838

    Degree:Doctoral degree

    Status:Employed

    Alma Mater:中南大学

    Discipline:Chemistry
    Chemical Engineering and Technology

    Academic honors:
    2015elected:Special Government Allowances
    Honors and Titles:
    2015-01-29elected:国务院政府特殊津贴
    2019-07-01elected:2018年度湖南省“优秀研究生导师”
    2017-11-21elected:世纪海翔杰出教师奖
    2020-04-10elected:湖南省自然科学二等奖(排名1)
    2014-01-21elected:湖南省发明二等奖(排名2)
  • Profile

    陈晓青,女,博士,二级教授,博士生导师,享受国务院政府特殊津贴。中南大学“531”二层次人才,“食品药品分子科学研究中心”主任。致力于生物、环境复杂体系分离分析,手性对映体识别与分离分析,生物、环境与食品安全及时检测(POCT)的研发。在Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun., Org. Lett. 等国际权威刊物上发表SCI收录论文300余篇,其中ESI高被引论文9篇(ORCID: 0000-0002-8768-8965)。主持承担国家自然科学基金面上项目7项、及其他纵、横向项目近40项。2019年获湖南省自然科学二等奖1项,2013年获湖南省发明二等奖1项,2003年获湖南省进步一等奖1项。授权发明专利9项。

    近年来代表性科研论文:
    2022:

    [1] Framework Nucleic Acid-Based Spatial-Confinement Amplifier for miRNA Imaging in Living Cells, Analytical Chemistry 2022, 94(6): 2934-2941

    [2] Facile construction of a reusable multi-enzyme cascade bioreactor for effective fluorescence discrimination and quantitation of amino acid enantiomers, Chemical Engineering Journal 2022, 428: 131975.

    2021:

    [1] Simultaneous In Situ Extraction and Self-Assembly of Plasmonic Colloidal Gold Superparticles for SERS Detection of Organochlorine Pesticides in Water, Analytical Chemistry 2021, 93(10): 4657-4665

    [2] AIEgen modulated per-functionalized flower-like IRMOF-3 frameworks with tunable light emission and excellent sensing properties, Chemical Communications 2021, 57: 2392-2395

    [3] Framework nucleic acid programmed combinatorial delivery nanocarriers for parallel and multiplexed analysis, Chemical Communications 2021, 57, 10935-10938

    [4] Photocatalytic Cyclization/Defluorination Domino Sequence to Access 3-Fluoro-1,5-dihydro-2H-pyrrol-2-one Scaffold, Organic Letters 2021, 23(12): 4754-4758

    [5] Phosphonium ylide-mediated programmable fluorination to access mono-and difluoromethylarenes, Organic Letters 2021, 23(7): 2538-2542

    [6] O-Perhalopyridin-4-yl Hydroxylamines: Amidyl-Radical Generation Scaffolds in Photoinduced Direct Amination of Heterocycles, Organic Letters 2021, 23(5): 1643-1647

    [7] Enantioselectivity-Switchable Organocatalytic [4+ 2]-Annulation to Access the Spirooxindole–Norcamphor Scaffold, Organic Letters 2021, 23(3): 963-968

    2020:
    [1] Integrating Target-Triggered Aptamer-Capped HRP@ Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics, Analytical Chemistry 2020, 92(20): 14259–14266.

    [2] l-Pyroglutamic Acid-Modified CdSe/ZnS Quantum Dots: A New Fluorescence-Responsive Chiral Sensing Platform for Stereospecific Molecular Recognition, Analytical Chemistry 2020, 92(17): 12040-12048.

    [3] “Pomegranate-like” plasmonic nanoreactors with accessible high-density hotspots for in situ SERS monitoring of catalytic reactions, Analytical Chemistry 2020, 92(5): 4115-4122.
    [4] Photoinduced Single‐Electron Transfer as an Enabling Principle in the Radical Borylation of Alkenes with NHC–Borane, Angewandte Chemie International Edition 2020, 59: 6706 –6710.

    [5] Photocatalytic C–F bond borylation of polyfluoroarenes with NHC-boranes, Organic Letters 2020, 22(5): 1742-1747.

    [6] Phosphine-mediated MBH-type/umpolung addition domino sequence: Divergent construction of coumarins, Organic Letters 2020, 22(2): 488-492.

    [7] AIE-active metal–organic frameworks: Facile preparation, tunable light emission, ultrasensitive sensing of copper (II) and visual fluorescence detection of glucose, Journal of Materials Chemistry C 2020, 8: 10408-10415

    2019:
    [1] Development of a “dual gates” locked, target-triggered nanodevice for point-of-care testing with a glucometer readout, ACS Sensors 2019, 4(4): 968-976.
    [2] Intelligent platform for simultaneous detection of multiple aminoglycosides based on a ratiometric paper-based device with digital fluorescence detector readout, ACS Sensors 2019, 4(12): 3283-3290.
    [3] Organocatalytic, Enantioselective, Polarity-Matched Ring-Reorganization Domino Sequence Based on the 3‑Oxindole Scaffold, Organic Letters 2019, 21(7): 2166-2170.
    [4] Photocatalytic, phosphoranyl radical-mediated N–O cleavage of strained cycloketone oximes, Organic Letters 2019, 21(8): 2658-2662.
    [5] Rapid and visual detection of aflatoxin B1 in foodstuffs using aptamer/G-quadruplex DNAzyme probe with low background noise, Food Chemistry 2019, 271: 581-587.
    2018:
    [1] Valency‐Controlled Framework Nucleic Acid Signal Amplifiers, Angewandte Chemie International Edition 2018, 57, 7131-7135.
    [2] Simultaneous in situ extraction and fabrication of surface-enhanced Raman scattering substrate for reliable detection of thiram residue, Analytical Chemistry 2018, 90(22): 13647-13654.
    [3] Visible-Light-Induced External Radical-Triggered Annulation To Access CF2-Containing Benzoxepine Derivatives, Organic Letters 2018, 20(5): 1363-1366.
    [4] Unraveling and manipulating the stereospecific retro-aldol reaction in the organocatalytic asymmetric aldol reaction of isatin and cyclohexanone, Organic Letters 2018, 20(23): 7535-7538.
    [5] 4-Mercaptophenylboronic acid-modified spirally-curved mesoporous silica nanofibers coupled with ultra performance liquid chromatography–mass spectrometry for determination of brassinosteroids in plants, Food Chemistry 2018, 263: 51-58.
    [6] A magnetic pH-induced textile fabric with switchable wettability for intelligent oil/water separation, Chemical Engineering Journal 2018, 347: 52-63.
    2017-2015:
    [1] Synthesis of multi-Au-nanoparticle-embedded mesoporous silica microspheres as self-filtering and reusable substrates for SERS detection, ACS Applied Materials & Interfaces 2017, 9(48): 42156-42166.
    [2] Discovery of temperature-dependent, autoinductive reversal of enantioselectivity: palladium-mediated [3+ 3]-annulation of 4-hydroxycoumarins, Chemical Communications 2017, 53(32): 4441-4444.
    [3] Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach, Food Chemistry 2017, 219: 321-328.
    [4] Amide-assisted intramolecular [3+ 2] annulation of cyclopropane ring-opening: a facile and diastereoselective access to the tricyclic core of (±)-scandine, Chemical Communications 2016, 52(10): 2177-2180.
    [5] Programmable engineering of a biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection, Angewandte Chemie International Edition 2015, 54(7): 2151-2155. 
    [6] Microbial biotransformation of bioactive flavonoids, Biotechnology Advances 2015, 33(1): 214-223
    [7] Visible-Light-Driven, Radical-Triggered Tandem Cyclization of o-Hydroxyaryl Enaminones: Facile Access to 3-CF2 /CF3-Containing Chromones, Organic Letters 2016, 19(1): 146-149.
    [8] Non-covalent interaction between dietary stilbenoids and human serum albumin: Structure–affinity relationship, and its influence on the stability, free radical scavenging activity and cell uptake of stilbenoids, Food Chemistry 2016, 202: 383-388.
    [9] Type 2 diabetes diminishes the benefits of dietary antioxidants: Evidence from the different free radical scavenging potential, Food Chemistry 2015, 186: 106-112.
    [10] Separation of polyphenols from leaves of Malus hupehensis (Pamp.) Rehder by off-line two-dimensional high speed counter-current chromatography combined with recycling elution mode, Food Chemistry 2015, 186: 139-145.
    [11] Separation of five flavonoids from tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) grains via off-line two dimensional high-speed counter-current chromatography, Food Chemistry 2015, 186: 153-159.
    [12] Macrocyclic β-cyclodextrin derivative-based aqueous-two phase systems: phase behaviors and applications in enantioseparation, Chemical Engineering Science 2016, 143: 1-11.


  • Research Field

  • Social Affiliations

    [1]  2017.12- 2022.12
    湖南省精密仪器测试学会第七届理事会  常务理事
    [2]  2017.12- 2022.12
    湖南省精密仪器测试学会色谱分会 副理事长
  • Education Background

    [1]  1986.9- 1989.6
    中南工业大学 | 分析化学 | Master's degree | Master's degree
    [2]  1982.9- 1986.6
    中南工业大学 | 冶金化学分析 | University graduated | Bachelor's degree
    [3]  2003.9- 2006.12
    中南大学 | 应用化学 | PhD Graduate | Doctoral degree
  • Work Experience

    [1]  2000.3- 2001.1
    日本东京工业大学 | 客座研究员
    [2]  1989.8- Now
    中南大学 | 化学化工学院 | 教授 | 在岗
  • Research Group

    Name of Research Group:药物合成与分离分析

    Description of Research Group:团队目前有教授6名,副教授1名,讲师1名。在校博士研究生17名,硕士研究生42名。

  • Other Contact Information

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