李珂

硕士生导师

入职时间:2022-04-11

所在单位:化学化工学院

学历:博士研究生毕业

办公地点:化学楼113

性别:男

学位:博士学位

在职信息:在职

毕业院校:湖南大学

   

论文成果

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(1)  Ke Li, Yifan Lyu, Yan Huang, Shuai Xu, Hongwen Liu, Lanlan Chen, Tianbing Ren, Mengyi Xiong, Shuangyan Huan, Lin Yuan, Xiao-Bing Zhang*, and Weihong Tan. A de novo strategy to develop NIR precipitating fluorochrome for long-term in situ cell membrane bioimaging. Proc. Natl. Acad. Sci. USA. 2021, 118, e2018033118.  

(2)  Ke Li, Tianbing Ren, Shuangyan Huan, Lin Yuan*, Xiao-Bing Zhang*. Progress and perspective of solid-state fluorophores for biomedical applications. J. Am. Chem. Soc. 2021, 143, 21143–21160. 

(3)  Ke Li, Shuai Xu, Mengyi Xiong, Shuangyan Huan, Lin Yuan*, Xiao-Bing Zhang*. Molecular engineering of organic-based agents for in situ bioimaging and phototherapeutics. Chem. Soc. Rev. 2021, 50, 11766-11784. 

(4) Ke Li, Xiaoxiao Hu, Hongwen Liu*, Shuai Xu, Shuangyan Huan*, Junbin Li, Tanggang Deng, Xiao-Bing Zhang* In situ imaging of furin activity with a highly stable probe by releasing of precipitating fluorochrome. Anal. Chem. 2018, 90, 11680-11687.

(5) Ke Li , Shuai Xu , Benhua Wang, Shuangyan Huan , Xiangzhi Song , Lin Yuan*, Xiaobing Zhang*.A Controllable Self-Localized Imaging Strategy Capable of Synchronous in Situ Tracking of Local Changes in Intracellular Bioactive Small-Molecules. SCIENCE CHINA Chemistry, 2023, doi.org/10.1007/s11426-023-1648-1.

(6) Shaohui, Han;  Hong,Wang,;   Haipu Li; Ke Li*; Jianxiu Wang*; Xiangzhi Song*. Construction of Dual-Functional, Reversible, Ratiometric, Golgi-Targeting Fluorescent Probe for Real-time Monitoring of Dynamics of Intracellular Redox Homeostasis. Anal. Chem. 2023, 95, 8002–8010.

(7) Haoming Chen,  Ke Li*, Lin Yuan and Xiao-Bing Zhang. Design of a near-infrared fluoro-photoacoustic probe for rapid imaging of carboxylesterase in liver injury. Chem. Comm., 2023,  doi.org/10.1039/D3CC03170E.

(8) Kun Chen, Shuai Xu, Zhiling Song, Ke Li*. Trimethyl Lock Quinone-Based Organic Molecular Probes for NQO1 Sensing and Imaging. Chemosensors 2023, 11, 221.

(9) Shuangyan Huan*, Ke Li, Xiaobing Zhang, Weiping Luo, Yuzhi Wang, Xia Yin, Tianbing Ren, Hongxia Gao, Zhiwu Liang. Virtual Simulation Experiment for the Design and Exploration of Tumor in Situ Fluorescence Labeling Technology. University Chemistry2023, 2303056. 

(10) Hongwen Liu, Ke Li, Xiaoxiao Hu, Longmin Zhu, Qiming Rong, Yongchao Liu, Xiao-Bing Zhang,* Jens Hasserodt, Feng-Li Qu, Weihong Tan. In situ localization of enzyme activity in live cells by a molecular probe releasing a precipitating fluorochrome. Angew. Chem. Int. Ed. 2017, 56, 11788-11792.

(11)  Hong-Wen Liu, Xiao-Xiao Hu, Ke Li, Yongchao Liu, Qiming Rong, Longmin Zhu, Lin Yuan, Feng-Li Qu*, Xiao-Bing Zhang*, Weihong Tan. A mitochondrial-targeted prodrug for NIR imaging guided and synergetic NIR photodynamic-chemo cancer therapy. Chem. Sci. 2017,8, 7689-7695. 

(12) Longmin Zhu, Hongwen Liu, Yue Yang, Xiaoxiao Hu, Ke Li, Shuai Xu, Jun-Bin Li, Guoliang Ke, Xiao-Bing Zhang*. Near-infrared fluorescent furin probe for revealing the role of furin in cellular carcinogenesis and specific cancer imaging. Anal. Chem. 2019, 91, 9682-9689.