马龙

教授 博士生导师 硕士生导师

入职时间:2009-08-18

所在单位:生命科学学院

学历:博士研究生毕业

性别:男

联系方式:Tel: +86-0731-84805352 Email: malong@sklmg.edu.cn

学位:博士学位

在职信息:在职

毕业院校:北京大学;中国医学科学院;德克萨斯大学西南医学中心

   

发表论文

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2010


Ma L.*, Reis G.*, Parada L.F., Schuman E.M. (1999). Neuronal NT-3 is not required for synaptic transmission or long-term potentiation in area CA1 of the adult mouse hippocampus. Learning & Memory,6: 267-275. (* Equal contribution)

 

Ma L., Merenmies J., Parada L.F. (2000). Molecular characterization of the TrkA/NGF receptor minimal enhancer reveals regulation by multiple cis elements to drive embryonic neuron expression. Development,127: 3777-3788.

 

Lei L., Ma L., Nef S., Thai T., Parada L.F. (2001). mKLF7, a potential transcriptional regulator of TrkA nerve growth factor receptor expression in sensory and sympathetic neurons. Development 128:1147-1158.

 

Ma L., Harada T., Harada C., Romero M.I., Hebert J.M., McConnell, S.K., Parada L.F. (2002). Neurotrophin-3 is required for appropriate establishment of thalamocortical connections. Neuron 36: 623-34.

 

Ma L., Lei L., Raisa Eng S., Turner E., Parada L.F. (2003). Brn3a regulation of TrkA/NGF receptor expression in developing sensory neurons. Development 130: 3525-34.

 

Lush M., Ma L. Parada L.F. (2005). TrkB signaling regulates the developmental maturation of the somatosensory cortex. Int J Dev Neurosci 23(6): 523-36.

 

Ma L., Horvitz H.R. (2009). Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3′ splice site in vivoPLOS Genet 5(11): e1000708. doi:10.1371/journal.pgen.1000708

 

Wang F., Huang S., Ma L.* (2010). Caenorhabditis elegans operons contain a higher proportion of genes with multiple transcripts and use 3′ splice sites differentially. PLOS ONE 5(8): e12456. doi:10.1371/journal.pone.0012456 (* Corresponding author)

 

2011-2015

 

Ma L.*, Tan Z.*, Teng Y., Hoersch S., Horvitz H.R. (2011). In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegansRNA 17(11): 2001-11 (* Equal contribution)

 

Lu J, Tan J, Durairajan S, Liu L, Zhang Z, Ma L, Shen H, Chan H, Li M. (2012). Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy. Autophagy8(1): 98-108.

 

Ma L.*, Gao X., Luo J., Huang L., Teng Y., Horvitz H.R.* (2012). The Caenorhabditis elegans gene mfap-1encodes a nuclear protein that affects alternative splicing. PLOS Genet 8(7): e1002827. doi:10.1371/journal.pgen.1002827 (* Co-corresponding authors)

 

de la Cruz I.P., Ma L., Horvitz H.R. (2014). The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. PLOS Genet 10(2): e1004175. doi:10.1371/journal.pgen.1004175.

 

Yuan D., Zhu Z., Tan X., Liang J., Zeng C., Zhang J., Chen J., Ma L., Dogan A., Brockmann G., Medina E., Rice A.D., Moyer R.W., Man X., Yi K., Li Y., Lu Q., Huang Y., and Huang S. (2014). Scoring the collective effects of SNPs: associations of minor alleles with complex traits in model organisms. Sci China Life Sci. 10.1007/s11427-014-4704-4 

 

Edens B.M., Ajroud-Driss S., Ma L., Ma Y.C. (2014). Molecular mechanisms and animal models of spinal muscular atrophy. BBA - Molecular Basis of Disease (Review) 1852(4): 685-692.

 

Gao X., Teng Y., Luo J., Huang L., Li M., Zhang Z., Ma Y.C., Ma L.* (2014). The survival motor neuron gene smn-1 interacts with the U2AF large subunit gene uaf-1 to regulate Caenorhabditis elegans lifespan and motor functions. RNA Biology 11(9): 1148-60. (* Corresponding author)

 

Xu Z., Luo J., Li Y., Ma L.* (2015). The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in C. elegans. G3: Genes, Genomes, Genetics 5(2): 195-203. (* Corresponding author)

 

Luo J., Xu Z., Tan Z., Zhang Z., Ma L.* (2015). Neuropeptide receptors NPR-1 and NPR-2 regulate C. elegans avoidance response to the plant stress hormone methyl salicylate. Genetics 199(2): 523-31. (* Corresponding author)

 

Miller N., Feng Z., Edens B., Yang B., Shi H., Sze C., Hong B., Su S., Cantu J., Topczewski J., Crawford T., Ko C.P., Sumner C., Ma L., Ma Y. C. (2015). Non-aggregating tau phosphorylation by Cdk5 contributes to motor neuron degeneration in spinal muscular atrophy. Journal of Neuroscience 35(15): 6038-50. 

 

2016-2020

 

Wu B., Xiao K., Zhang Z., Ma L.* (2016). Altered expression of EPO might underlie hepatic hemangiomas in LRRK2 knockout mice. BioMed Research International

Article ID 7681259. (* Corresponding author)

 

Wei X., Gao H., Zou J., Liu X., Chen D., Liao J., Xu Y., Ma L., Tang B., Zhang Z., Cai X., Jin K., Xia Y.,Wang Q. (2016). Contra-directional coupling of Nur77 and Nurr1 in neurodegeneration: A novel mechanism for memantine-induced anti-inflammation and anti-mitochondrial Impairment. Mol Neurobiol 53(9): 5876-5892

 

Liu R., Gao Y., Ma L. (2016). Applying pharmacogenomics in therapeutics. Chapter 2: Principles of pharmacogenetic biotechnology and testing in clinical practice (Book Chapter). Editor: Xiaodong Feng, Hong-Guang Xie. CRC Press, Taylor and Francis Group.

 

Zhou C., Gao X., Hu S., Gan W., Xu J., Ma Y.C., Ma L.* (2018). RBM-5 modulates U2AF large subunit-dependent alternative splicing in C. elegansRNA biology 15(10): 1295-1308. (* Corresponding author)

 

Xu Z., Hu Y., Deng Y., Chen Y., Hua H., Huang S., Nie Q., Pan Q., Ma D.K., Ma L.* (2018). WDR-23 and SKN-1/Nrf2 Coordinate with the BLI-3 Dual Oxidase in Response to Iodide-Triggered Oxidative Stress. G3: Genes, Genomes, Genetics 8(11): 3515-3527. (* Corresponding author)

 

Tan Z.*, Zeng H., Xu Z., Tian Q., Gao X., Zhou C., Zheng Y., Wang J., Ling G., Wang B., Yang Y., Ma L. *(2018). Identification of ANKDD1B variants in an ankylosing spondylitis pedigree and a sporadic patient. BMC Medical Genetics 19(1): 1-9. (* Co-corresponding authors)

 

Gao X., Xu J., Chen H., Xue D., Pan W., Zhou C., Ma Y.C.*, Ma L.* (2019). Defective Expression of Mitochondrial, Vacuolar H+-ATPase and Histone Genes in a C. elegans Model of SMA. Frontiers in genetics 10: 410. (* Co-corresponding authors)

 

Zhou C., Luo J., He X., Zhou Q., He Y., Wang X., Ma L.* (2020). The NALCN Channel Regulator UNC-80 Functions in a Subset of Interneurons to Regulate Caenorhabditis elegans Reversal Behavior. G3: Genes, Genomes, Genetics 10(1): 199-210. (* Corresponding author)

 

2021- 

Zhou C., Zhou Q., He X., He Y., Wang X., Zhu X., Zhang Y., Ma L.* (2022) Differential modulation of C. elegans motor behavior by NALCN and two-pore domain potassium channels. PLOS Genet 18(4): e1010126(* Corresponding author)

 

Yang S., Nie T., She H., Tao K., Lu F., Hu Y., Huang L., Zhu L., Feng D., He D., Qi J., Kukar T., Ma L., Mao Z., Yang Q. (2022) Regulation of TFEB nuclear localization by HSP90AA1 promotes autophagy and longevityAutophagy DOI: 10.1080/15548627.2022.2105561

 

Huang Z., Ma L., Mishra A., Turnball JE., Tu H. (2022) C. elegans as an emerging model of pharmacological innovation. Frontiers in Pharmacology 13. (Editorial).

 

Hu Y., Xu Z., Pan Q., Ma L. * (2023) Casein kinase 1 gamma regulates oxidative stress response via interacting with the NADPH dual oxidase complex. PLOS Genet 19(4): e1010740. (* Corresponding author)

 

Kang J., Huang G., Ma L., Tong Y., Chen P., Shen J. (2023) Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival. eLife 12: RP92673