Influence of filtration during sample pretreatment on the detection of antibiotics and non-steroidal anti-inflammatory drugs in natural surface waters
点击次数：
影响因子：
5.92
DOI码：
10.1016/j.scitotenv.2018.08.437
发表刊物：
The Science of the total environment
关键字：
Filter materials, Multi-residue analysis, Pharmaceuticals, Preservatives, Water matrices
摘要：
Owing to the ease and effectiveness of removing suspended substances (SSs), filtration has become a universal pretreatment step during water sample preparation. However, it can lead to the underestimation of contaminants if the targets easily associate with the SSs or filters. For the first time, this study comprehensively assessed issues related to filtration for the accurate quantification of 35 typical pharmaceuticals, including 28 antibiotics and seven non-steroidal anti-inflammatory drugs (NSAIDs), in water samples by comparing the effects of different filter materials, preservatives, and water matrices on the recoveries. The results showed that some sulfonamides and NSAIDs had an affinity for nylon filters, whereas trimethoprim and macrolides were easily retained on mixed cellulose ester filters. The use of glass fiber filter (0.7 mum) resulted in improved recovery of all the targets. Acidification promoted the adsorption of fluoroquinolones, tylosin, and roxithromycin on SSs, whereas 5% methanol resulted in desorption of macrolides from the SSs and other pharmaceuticals (sulfadiazine, trimethoprim, etc.) from the solid-phase extraction cartridges. Without additional detection of targets adsorbed on the SSs and filters, the addition of appropriate surrogates prior to filtration can help correct the loss. Copyright © 2018 Elsevier B.V. All rights reserved.
论文类型：
期刊论文
学科门类：
环境科学与工程
文献类型：
J
卷号：
650
页面范围：
769-778
ISSN号：
1879-1026
是否译文：
否
学位：博士学位
职称：副教授
学科：化学工程与技术
所在单位：化学化工学院