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MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation

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Release time:2016-04-13
Affiliation of Author(s):Department of Oncology, Xiangya Hospital, Central South University
Journal:Molecular and cellular biochemistry
Place of Publication:Netherlands
Key Words:Glioma miR-129-2 High-mobility group box 1 DNA methylation
Abstract:our data suggested that miR-129-2 functions as a tumor suppressor in glioma cells by directly targeting HMGB1 and is down-regulated by DNA methylation, which may provide a novel therapeutic strategy.
Co-author:Liangfang Shen, Xi Zhang, Junqiang Huang, Yu Yang
Indexed by:Unit Twenty Basic Research
Document Code:0300-8177(2015)1-2-0229-11
Discipline:临床医学
Document Type:J
Volume:404
Issue:1-2
Page Number:229-239
ISSN No.:0300-8177
Translation or Not:no
Date of Publication:2015-03-14

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