Personal Information

Songshu XIAO, M.D.

 

Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China

Tel: 86-731-88618021; Email: xiaosongshu@csu.edu.cn

 

APPOINTMENT

Professor, Obstetrics and Gynecology, 3^rd Xiangya Hospital, CSU                       2022-Present

Associate Professor, Obstetrics and Gynecology, 3^rd Xiangya Hospital, CSU         2015-2022

Visiting staff, Obstetrics and Gynecology, 3^rd Xiangya Hospital, CSU                    2009-2015

Resident, Obstetrics and Gynecology, 3^rd Xiangya Hospital, CSU                           2005-2009

 

RESEARCH INTERESTS

Gynecological tumors and specialises in many gynecologic minimally invasive techniques.

 

SELECTED PUBLICATIONS

1.       Yuan J, Xie H, Chen M, Zeng F, Xiao S*.2022. A case report of retroperitoneal ectopic pregnancy with lymphatic migration after in vitro fertilization-embryo transfer: an explanation to embryo distant migration，Fertil Steril, 118(3):598-600. 

2.       Yuan J, Lan H, Huang DQ ,Guo XH ,Liu C,Liu, SP,Zhang P,Cheng, Y*,Xiao S*,2022, Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer, Front Cell Dev Biol, 10, DOI: 10.3389/fcell.2022.852135

3.       Yuan J, Jiang X, Lan H, Zhang X, Ding T, Yang F, Zeng D, Yong J, Niu B*, Xiao S*.2022.Multi-Omics analysis of the therapeutic value of MAL2 based on data mining in human cancer.Front Cell Dev Biol.17;9:736649.

4.       Xie H#，Wan Y#，Yi S，Zeng F，Sun X，Yang Y，Xiao S*. 2022.Clinical analysis of 2152 cases of abnormal uterine bleeding treated by NovaSure endometrial ablation. Int J Gynecol Obstet, 158(2): 301-307. 

5.       Lan H,Yuan J, Chen X,Liu C,Guo X,Wang X,Song J,Cao K*,Xiao S*. 2021.Multiomics profiling of the expression and prognosis of MCMs in endometrial carcinoma，Biosci Rep. 22;41(12): BSR20211719.

6.       Chen X#, Lan H#, He D, Xu R, Zhang Y, Cheng Y,Chen H, Xiao S*, Cao K*.2021.Multi-Omics Profiling Identifies Risk Hypoxia-Related Signatures for Ovarian Cancer Prognosis. Front Immunol. 19;12:645839.

7.       Chen X#, Lan H#, He D, Wang Z, Xu R, Yuan J, Xiao M, Zhang Y, Gong L, Xiao S*, Cao K*. 2021.Analysis of autophagy-related signatures identified two distinct subtypes for evaluating the tumor immune microenvironment and predicting prognosis in ovarian cancer.Front Oncol. 10;11:616133.

8.       Lan H ,Yuan J , Zeng D,Liu C , Guo X , Yong J ,Zeng X *, Xiao S*. 2021.The emerging role of non-coding RNAs in drug resistance of ovarian cancer, Front Gene. 20;12:693259.

9.       Yong J,Guo X,Lan H,Yuan J,Zeng D, Zeng X,Yi S,Xiao S*.2021.Clinical analysis of the MyoSure hysteroscopic tissue removal system of endometrial polyps in women with an intact hymen.BMC Womens Health,21:214.

10.    Jiang X, Yuan J, Dou Y, Zeng D, Xiao S*.2021.Lipopolysaccharide Affects the Proliferation and Glucose Metabolism of Cervical Cancer Cells Through the FRA1/MDM2/p53 Pathway. Int J Med Sci 18(4):1030-1038. 

11.    Tian M , Chen X ,Li L ,Wu H ,Zeng D ,Wang X , Zhang  Y,  Xiao S*, Cheng Y*.2021.Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis.Acta Pharmacol Sin,42(7):1180-1189;

12.    Zhang M, Liang L, He J, He Z, Yue C, Jin X, Gao M, Xiao S*, Zhou Y*. 2020.Fra-1 Inhibits Cell Growth and the Warburg Effect in Cervical Cancer Cells via STAT1 Regulation of the p53 Signaling Pathway. Front Cell Dev Biol. 8:579629.

13.    Dou Y，Zeng D，Zou Z，Wan Y，Xu D，Xiao S*.2020.Hysteroscopic treatment of cesarean scar defect. Arch Gynecol Obstet. ,302(5):1215-1220.

14.    Zeng X , Yuan J, Wang C ,  Zeng D,Yong J , Jiang X,  Lan H,Xiao S*.2020.circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals.Mol Med, 26(1):70.

15.    Yuan J, Lan H, Jiang X, Zeng D,Xiao S*.2020.Bcl‑2 family: Novel insight into individualized therapy for ovarian cancer .Int J Mol Med, 46(4):1255-1265.

16.    Zhao C, She X, Zhang Y, Liu C, Li P, Chen S, Sai B, Li Y, Feng J, Liu J, Sun Y, Xiao S*, Li L*,Wu M*. 2020.LRRC4 Suppresses E-Cadherin- Dependent Collective Cell Invasion and Metastasis in Epithelial Ovarian Cancer. Front. Oncol. 10:144.

17.    Dou Y, Huang D, Zeng X, Zhou Y, Jiang X, Yue C, He J, Xiao S*.2020.All-trans retinoic acid enhances the effect of Fra-1 to inhibit 3 cell proliferation and metabolism in cervical cancer.Biotechnol Lett., DOI 10.1007/s10529-020-02847-8.

18.    Jiang X, Xie H, Dou Y, Yuan J, Zeng D, Xiao S*.2020.Expression and function of FRA1 protein in tumors, Molecular Biology Reports, 47(1):737-752.

19.    Xiao S, Li Y ,Pan Q, Ye M, He S, Tian Q, Xue M*. 2019. MiR-34c /SOX9 axis regulates the chemo-resistance of ovarian cancer cell to cisplatin (DDP)-based chemotherapy.J Cell Biochem, 120(3):2940-2953.

20.    Zeng X, Jiang X,Yuan J ,Yong J ,Zeng D ,Dou Y,Xie H ,Xiao S*. 2019.lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.Cancer Medicine.  8(16):7074-7085.

21.    Lazare C#, Xiao S#, Meng Y, Wang C, Li W, Wang Y, Chen G, Wei J, Hu J, Xue M* ,Wu P*,2019.Evaluation of Cervical Intraepithelial Neoplasia Occurrence Following the Recorded Onset of Persistent High-Risk Human Papillomavirus Infection: A Retrospective Study on Infection Duration. Front. Oncol.,9:976.

22.    Xiao S,Xie H,Zhu X,Li X,Yi S,Deng X,Xue M*.2019.Study on the Significance of Folate Receptor-Mediated Staining Solution (FRD) Staining in Screening High Grade Cervical Lesions.Med Sci Monit. 16;25:2792-2801.

23.    Zeng X,Xie H ,Yuan J , Jiang X,Yong J ,Zeng D ,Dou Y,Xiao S*.  2019.M2-like tumor-associated macrophages-secreted EGF promotes epithelial ovarian cancer metastasis via activating EGFR-ERK signaling and suppressing lncRNA LIMT expression.Cancer Biol ＆Ther.20(7):956-966.

24.    Dou Y, Jiang X, Xie H, He J, Xiao S*.2019.The Jun N-terminal kinases signaling pathway plays a“seesaw”role in ovarian carcinoma：A molecular aspect.J Ovarian Res.12:99.

 

25.    Wu H, Xiao J, Xiao S*, Cheng Y*.2019.KRAS: A promising therapeutic target for cancer treatment.Curr Top Med Chem.19(23): 2081-2097.

 

26.    Xiao S, Li Y ,Pan Q, Ye M, He S, Tian Q, Xue M*. MiR-34c/SOX9 axis regulates the chemoresistance of ovarian cancer cell to cisplatin (DDP)-based chemotherapy. J Cell Biochem, 2018 Dec 9.doi:10.1002/jcb.26865.

 

27.    Xiao S, Zhou Y, Yi W, Luo G, Jiang B, Tian Q, Li Y, Xue M*. 2015. Fra‑1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro. Int J Oncol, 46(4): 1677-1684.

 

28.    Xiao S, Fan J, He S, Li Y, Wang L, Yu K, Deng X, Xue M*. 2016. Analysis of human papillomavirus infection in 16,320 patients from a gynecology clinic in Central South China. J Low Genit Tract Dis, 20(4): 327-331.

 

29.    Xiao S, Mu Q, Wan Y, Xue M*. 2016. Spontaneous renal hemorrhage caused by invasive mole: A case report. Eur J Gynaecol Oncol, 37(3): 417-419.

 

30.    Xiao S, Zhou Y, Jiang J, Yuan L, Xue M*. 2014. CD44 affects the expression level of FOS‑like antigen 1 in cervical cancer tissues. Mol Med Rep, 9(5): 1667-1674.

 

31.    Xiao S, Wan Y, Xue M*, Zeng X, Xiao F, Xu D, Yang X，Zhang P, Sheng W, Xu J, Zhou S. 2014. Etiology, treatment, and reproductive prognosis of women with moderate-to-severe intrauterine adhesions. Int J Gynecol Obstet, 125(2): 121-124.

 

32.    Xiao S, Liao S, Zhou Y, Jiang B, Li Y, Xue M*. 2014. High expression of octamer transcription factor 1 in cervical cancer. Oncol Lett, 7(6): 1889-1894.

 

33.    Sun X, Xue M, Xiao S*, Wan Y, Wang B. 2010. Uterine diverticulum complicating pregnancy diagnosed by ultrasound and uteroscopy. Int J Gynecol Obstet, 109: 247-248.

 

34.    Xiao S, Xue M*, Wan Y, Su Z. 2011. Gynandroblastoma with the symptoms of infertility and secondary amenorrhea:one case report. Clin Exp Obstet Gynecol, 38(4): 419-420.

 

35.   Xiao S, Tian Q, Xue M*. 2014. Infertility caused by intrauterine fetal bone retention: A case report. J Med Case Rep, 8: 177.

 

36.    Xiao S, Xue M*, Wan Y, Xu D. 2014. Hysteroscopy- and laparoscopy-based diagnosis and treatment of girls with unbroken hymen with an obstructing uterine septum: two case reports. J Med Case Rep, 8: 222.

 

37.    Xiao S, Xue M*, Deng X, Wan Y. 2011. Occurrence of multiple Mullerian adenocele inside the uterine body. J Gynecol Surg, 27(1): 43-44.

 

38.    Xiao S, Lei R, Xue M*. 2013. Primary teratoma in preperitoneal space: Case report and literature review. J Gynecol Surg, 29(5): 248-250.

 

39.    Guan Y, Jiang S, Yu P, Wen M, Zhang Y, Xiao S*, Xu X*, Cheng Y*. 2018. Suppresion of eEF-2K-mediated autophagy enhances the cytotoxicity of Raddeanin A against human breast cancer cells in vitro. Acta Pharmacol Sin, 39(4): 642-648.