陈晓青

教授 博士生导师 硕士生导师

所在单位:化学化工学院

学历:博士研究生毕业

办公地点:湖南省长沙市潇湘中路中南大学新校区化学化工学院345

性别:女

联系方式:邮箱:xqchen@csu.edu.cn 电话:13974833838

学位:博士学位

在职信息:在职

毕业院校:中南大学

学科:化学
化学工程与技术

学术荣誉:

2015  当选:  政府特贴

曾获荣誉:

2015-01-29  当选:  国务院政府特殊津贴

2019-07-01  当选:  2018年度湖南省“优秀研究生导师”

2017-11-21  当选:  世纪海翔杰出教师奖

2020-04-10  当选:  湖南省自然科学二等奖(排名1)

2014-01-21  当选:  湖南省发明二等奖(排名2)

个人简介

陈晓青,女,博士,二级教授,博士生导师,享受国务院政府特殊津贴。中南大学“531”二层次人才,“食品药品分子科学研究中心”主任。致力于生物、环境复杂体系分离分析,手性对映体识别与分离分析,生物、环境与食品安全及时检测(POCT)的研发。在Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun., Org. Lett. 等国际权威刊物上发表SCI收录论文300余篇,其中ESI高被引论文9篇(ORCID: 0000-0002-8768-8965)。主持承担国家自然科学基金面上项目7项、及其他纵、横向项目近40项。2019年获湖南省自然科学二等奖1项,2013年获湖南省发明二等奖1项,2003年获湖南省进步一等奖1项。授权发明专利9项。

近年来代表性科研论文:
2022:

[1] Framework Nucleic Acid-Based Spatial-Confinement Amplifier for miRNA Imaging in Living Cells, Analytical Chemistry 2022, 94(6): 2934-2941

[2] Facile construction of a reusable multi-enzyme cascade bioreactor for effective fluorescence discrimination and quantitation of amino acid enantiomers, Chemical Engineering Journal 2022, 428: 131975.

2021:

[1] Simultaneous In Situ Extraction and Self-Assembly of Plasmonic Colloidal Gold Superparticles for SERS Detection of Organochlorine Pesticides in Water, Analytical Chemistry 2021, 93(10): 4657-4665

[2] AIEgen modulated per-functionalized flower-like IRMOF-3 frameworks with tunable light emission and excellent sensing properties, Chemical Communications 2021, 57: 2392-2395

[3] Framework nucleic acid programmed combinatorial delivery nanocarriers for parallel and multiplexed analysis, Chemical Communications 2021, 57, 10935-10938

[4] Photocatalytic Cyclization/Defluorination Domino Sequence to Access 3-Fluoro-1,5-dihydro-2H-pyrrol-2-one Scaffold, Organic Letters 2021, 23(12): 4754-4758

[5] Phosphonium ylide-mediated programmable fluorination to access mono-and difluoromethylarenes, Organic Letters 2021, 23(7): 2538-2542

[6] O-Perhalopyridin-4-yl Hydroxylamines: Amidyl-Radical Generation Scaffolds in Photoinduced Direct Amination of Heterocycles, Organic Letters 2021, 23(5): 1643-1647

[7] Enantioselectivity-Switchable Organocatalytic [4+ 2]-Annulation to Access the Spirooxindole–Norcamphor Scaffold, Organic Letters 2021, 23(3): 963-968

2020:
[1] Integrating Target-Triggered Aptamer-Capped HRP@ Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics, Analytical Chemistry 2020, 92(20): 14259–14266.

[2] l-Pyroglutamic Acid-Modified CdSe/ZnS Quantum Dots: A New Fluorescence-Responsive Chiral Sensing Platform for Stereospecific Molecular Recognition, Analytical Chemistry 2020, 92(17): 12040-12048.

[3] “Pomegranate-like” plasmonic nanoreactors with accessible high-density hotspots for in situ SERS monitoring of catalytic reactions, Analytical Chemistry 2020, 92(5): 4115-4122.
[4] Photoinduced Single‐Electron Transfer as an Enabling Principle in the Radical Borylation of Alkenes with NHC–Borane, Angewandte Chemie International Edition 2020, 59: 6706 –6710.

[5] Photocatalytic C–F bond borylation of polyfluoroarenes with NHC-boranes, Organic Letters 2020, 22(5): 1742-1747.

[6] Phosphine-mediated MBH-type/umpolung addition domino sequence: Divergent construction of coumarins, Organic Letters 2020, 22(2): 488-492.

[7] AIE-active metal–organic frameworks: Facile preparation, tunable light emission, ultrasensitive sensing of copper (II) and visual fluorescence detection of glucose, Journal of Materials Chemistry C 2020, 8: 10408-10415

2019:
[1] Development of a “dual gates” locked, target-triggered nanodevice for point-of-care testing with a glucometer readout, ACS Sensors 2019, 4(4): 968-976.
[2] Intelligent platform for simultaneous detection of multiple aminoglycosides based on a ratiometric paper-based device with digital fluorescence detector readout, ACS Sensors 2019, 4(12): 3283-3290.
[3] Organocatalytic, Enantioselective, Polarity-Matched Ring-Reorganization Domino Sequence Based on the 3‑Oxindole Scaffold, Organic Letters 2019, 21(7): 2166-2170.
[4] Photocatalytic, phosphoranyl radical-mediated N–O cleavage of strained cycloketone oximes, Organic Letters 2019, 21(8): 2658-2662.
[5] Rapid and visual detection of aflatoxin B1 in foodstuffs using aptamer/G-quadruplex DNAzyme probe with low background noise, Food Chemistry 2019, 271: 581-587.
2018:
[1] Valency‐Controlled Framework Nucleic Acid Signal Amplifiers, Angewandte Chemie International Edition 2018, 57, 7131-7135.
[2] Simultaneous in situ extraction and fabrication of surface-enhanced Raman scattering substrate for reliable detection of thiram residue, Analytical Chemistry 2018, 90(22): 13647-13654.
[3] Visible-Light-Induced External Radical-Triggered Annulation To Access CF2-Containing Benzoxepine Derivatives, Organic Letters 2018, 20(5): 1363-1366.
[4] Unraveling and manipulating the stereospecific retro-aldol reaction in the organocatalytic asymmetric aldol reaction of isatin and cyclohexanone, Organic Letters 2018, 20(23): 7535-7538.
[5] 4-Mercaptophenylboronic acid-modified spirally-curved mesoporous silica nanofibers coupled with ultra performance liquid chromatography–mass spectrometry for determination of brassinosteroids in plants, Food Chemistry 2018, 263: 51-58.
[6] A magnetic pH-induced textile fabric with switchable wettability for intelligent oil/water separation, Chemical Engineering Journal 2018, 347: 52-63.
2017-2015:
[1] Synthesis of multi-Au-nanoparticle-embedded mesoporous silica microspheres as self-filtering and reusable substrates for SERS detection, ACS Applied Materials & Interfaces 2017, 9(48): 42156-42166.
[2] Discovery of temperature-dependent, autoinductive reversal of enantioselectivity: palladium-mediated [3+ 3]-annulation of 4-hydroxycoumarins, Chemical Communications 2017, 53(32): 4441-4444.
[3] Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach, Food Chemistry 2017, 219: 321-328.
[4] Amide-assisted intramolecular [3+ 2] annulation of cyclopropane ring-opening: a facile and diastereoselective access to the tricyclic core of (±)-scandine, Chemical Communications 2016, 52(10): 2177-2180.
[5] Programmable engineering of a biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection, Angewandte Chemie International Edition 2015, 54(7): 2151-2155. 
[6] Microbial biotransformation of bioactive flavonoids, Biotechnology Advances 2015, 33(1): 214-223
[7] Visible-Light-Driven, Radical-Triggered Tandem Cyclization of o-Hydroxyaryl Enaminones: Facile Access to 3-CF2 /CF3-Containing Chromones, Organic Letters 2016, 19(1): 146-149.
[8] Non-covalent interaction between dietary stilbenoids and human serum albumin: Structure–affinity relationship, and its influence on the stability, free radical scavenging activity and cell uptake of stilbenoids, Food Chemistry 2016, 202: 383-388.
[9] Type 2 diabetes diminishes the benefits of dietary antioxidants: Evidence from the different free radical scavenging potential, Food Chemistry 2015, 186: 106-112.
[10] Separation of polyphenols from leaves of Malus hupehensis (Pamp.) Rehder by off-line two-dimensional high speed counter-current chromatography combined with recycling elution mode, Food Chemistry 2015, 186: 139-145.
[11] Separation of five flavonoids from tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) grains via off-line two dimensional high-speed counter-current chromatography, Food Chemistry 2015, 186: 153-159.
[12] Macrocyclic β-cyclodextrin derivative-based aqueous-two phase systems: phase behaviors and applications in enantioseparation, Chemical Engineering Science 2016, 143: 1-11.


教育经历

[1]   1986.9-1989.6

中南工业大学  |  分析化学  |  硕士学位  |  硕士研究生毕业

[2]   1982.9-1986.6

中南工业大学  |  冶金化学分析  |  学士学位  |  大学本科毕业

[3]   2003.9-2006.12

中南大学  |  应用化学  |  博士学位  |  博士研究生毕业

工作经历

[1]   2000.3-2001.1

日本东京工业大学  |  客座研究员

[2]   1989.8-至今

中南大学  |  化学化工学院  |  教授  |  在岗

社会兼职

  • [1]   2017.12-2022.12    
    湖南省精密仪器测试学会第七届理事会  常务理事

  • [2]   2017.12-2022.12    
    湖南省精密仪器测试学会色谱分会 副理事长

团队成员

团队名称:药物合成与分离分析

团队介绍:团队目前有教授6名,副教授1名,讲师1名。在校博士研究生17名,硕士研究生42名。

阳华

  

蒋新宇

  

焦飞鹏

  

施树云

  

于金刚

  

向皞月

  

刘琦