Language : English
杨艳婧
  • Personal Information

    Distinguished Associate Professor



    Supervisor of Master's Candidates

    Date of Employment:2017-09-20

    School/Department:Chemistry and Chemical Engineering

    Education Level:PhD Graduate

    Sex:Female

    Degree:Doctoral degree

    Status:Employed

    Alma Mater:湖南大学

    Discipline:Chemistry

    Honors and Titles:
    2019-10-21elected:湖南省优秀毕业生
    2019-10-21elected:湖南省优秀博士学位论文
  • Profile

           杨艳婧,女,博士,硕士生导师,主要从事“纳米尺度上的生物分析化学”、“纳米药物递送”等研究工作。在基因检测、DNA机器、信号放大、分子探针设计、细胞原位分析、疾病早期诊断及纳米药物抗肿瘤研究等方面取得了一系列研究成果。 迄今为止,在 JACS、Angew. Chem. Int. Ed.、ACS Nano、Chem. Sci.、Anal. Chem.、Chem. Commun.等杂志上发表论文50余篇,其中高被引论文1篇,IF>6分论文20篇,JCR一区论文40篇,应邀撰写综述2篇, 论文总他引次数 1181次,单篇最高他引 226 次,H-index 达17。曾获得湖南省优秀博士学位论文奖,国家奖学金,校长奖学金,并先后主持国家自然科学基金,湖南省自然科学基金等项目。


    科研成果:

    1.教学科研项目

    国家自然科学基金面上项目,遗传编码的荧光RNA适配体探针用于脑活性分子成像研究,54万,主持;

    国家自然科学青年基金,基于多功能DNA纳米探针的癌症治疗与疗效原位评估研究,24万,主持;

    湖南省自然科学基金,基于碳量子点和DNA的比率型探针在细胞表面的应用研究,5万,主持;

    中央高校基本科研业务专项基金,特聘副教授,80万,主持;

    化学生物传感与计量学国家重点实验室(湖南大学)开放课题,3万,主持。

    中南大学教学改革项目,基于OBE理念协同培养创新性人才的《药用高分子材料》教学改革研究,2万,主持。

    广西壮族自治区科技厅广西科技基地和人才专项,165万,在研,参与。

    国家自然科学基金面上项目,抗原蛋白-分子印迹荧光可视化载体体系的精准构筑及其分离机制研究,54万,参与。



    2. 获得奖励

    湖南省优秀博士学位论文奖;

    中南大学第十一届“三十佳”课堂教学竞赛“三十佳”荣誉称号。


    3. 代表性论文
    (1)  Yanjing Yang; Tong Luo; Yao HeZhiwei Deng;Jiacheng Li; Hui Liu; Jing Nie; De Wang; Jin Huang*;  Shian Zhong*; Nanoflare Couple: Multiplexed mRNA Imaging and Logic-Controlled Combinational Therapy,Analytical Chemistry,2022, 94(35): 12204-12212.

    (2) Tong Luo; Jiacheng Li; Yao He; Hui Liu; Zhiwei Deng; Xi Long; Qingqing Wan; Jiacheng Ding; Zan Gong; Yanjing Yang*;  Shian Zhong*; Designing a CRISPR/Cas12a- and Au-Nanobeacon-Based Diagnostic Biosensor Enabling Direct, Rapid, and Sensitive miRNA Detection, Analytical Chemistry, 2022, 94(17): 6566–6573.

    (3) Zhiwei Deng; Jiacheng Li; Hui Liu; Tong Luo; Yanjing Yang*; Minghui Yang*; Xiang Chen*; A light-controlled DNA nanothermometer for temperature sensing in the cellular membrane microenvironment, Biosensors and Bioelectronics, 2022: 114627.

    (4) Jiacheng Li; Tong Luo; Yao He; Hui Liu; Zhiwei Deng; Jiaqi Bu; Xi Long; Shian Zhong*; Yanjing Yang*; Discovery of the Rnase activity of CRISPR–Cas12a and its distinguishing cleavage efficiency on various substrates, Chemical Communications , 2022, 58: 2540-2543.

    (5) Tianhao Li; Zhiwei Deng; Jiaqi Bu; Hui Liu; Yanjing Yang*; Shian Zhong*; Quantum dot based molecularly imprinted polymer test strips for fluorescence detection of ferritin, Sensors and Actuators: B. Chemical , 2022, 358:131548.

    (6) Zhiwei Deng; Peiru Gao; Hui Liu; Yao He; Shian Zhong; Yanjing Yang*; Cell-Surface-Anchored DNA Sensors for Simultaneously Monitoring Extracellular Sodium and Potassium Levels, Analytical Chemistry , 2021, 93(49): 16432-16438.

    (7) Yanjing Yang;  Yao He; Zhiwei Deng; Jiacheng, Li; Jin Huang; Shian Zhong*. Intelligent Nanoprobe: Acid-Responsive Drug Release and In Situ Evaluation of Its Own Therapeutic Effect.  Analytical chemistry, 2020, 92, 12371-12378. 

    (8) Deng, Zhiwei; Li, Xiufang; Liu, Hui; He, Yao; Zhang, Jie; Yuan, Jing; Gao, Peiru; Jiang, Xuling; Yang, Yanjing;* Zhong, Shian.* A nanoprobe for ratiometric imaging of glutathione in living cells based on the use of a nanocomposite prepared from dual-emission carbon dots and manganese dioxide nanosheets. Microchimica Acta. 2020, 187, 537.

    (9) Yuan, Jing; Deng, Zhiwei; Liu, Hui; Li, Xiufang; Li, Jianbing; He, Yao; Qing, Zhihe; Yanjing Yang;*  Zhong, Shian.* Cell-Surface-Anchored Ratiometric DNA Nanoswitch for Extracellular ATP Imaging. ACS SENSORS. 2019, 4, 1648-1653.

    (10) Yanjing Yang, Jin Huang,* Xiaohai Yang, Xiaoxiao He, Ke Quan, Nuli Xie, Min Ou, Kemin Wang.* Gold nanoparticle based hairpin-locked-DNAzyme probe for amplified miRNA imaging in living cells. Analytical chemistry, 2017, 89, 5850−5856.

    (11) Yanjing Yang, Jin Huang,* Xiaohai Yang, Ke Quan, He Wang, Le Ying, Nuli Xie, Min Ou, and Kemin Wang*. An aptazyme-gold nanoparticle sensor for amplified molecular probing in living Cells. Analytical chemistry, 2016, 88, 5981-5987. 

    (12) Yanjing Yang, Jin Huang,* Xiaohai Yang, Ke Quan, Nuli Xie, Min Ou, Jinlu Tang and Kemin Wang*. Aptamer-based FRET nanoflares for imaging potassium ions in living cells. Chemical Communications, 2016, 52, 11386-11389.
    (13) Le Ying, Nuli Xie, Yanjing Yang,* Xiaohai Yang, Qifeng Zhou, Bincheng Yin, Jin Huang,* and Kemin Wang*. A cell-surface-anchored ratiometric i-motif sensor for extracellular pH detection. Chemical Communications, 2016, 52, 7818-7821.

    (14) Yanjing Yang, Jin Huang, Xiaohai Yang, Ke Quan, He Wang, Le Ying, Nuli Xie, Min Ou, and Kemin Wang*. FRET nanoflares for intracellular mRNA detection: avoiding false positive signals and minimizing effects of system fluctuations. Journal of the American Chemical Society, 2015, 137, 8340-8343.

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  • Education Background

    [1]  2012.9- 2017.6
    湖南大学 | 化学 | PhD Graduate | Doctoral degree
  • Work Experience

    [1]  中南大学 | 化学化工学院
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  • Other Contact Information

     Email:yangyanjing@csu.edu.cn