Bioactivity of SiOC and SiCaMgOC coatings prepared by sol-gel method
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Release time:2023-08-12 DOI number:10.1016/j.ceramint.2023.08.138 Journal:Ceramics International Key Words:Bioactivity
SiOC
Ca- and Mg-modiffed silicon oxycarbide
Cytotoxicity Abstract:SiOC and SiCaMgOC coatings were prepared by sol–gel method from precursors of hydrosilane and the mixture
of hydrosilane, calcium acetylacetonate (Ca(acac)2) and magnesium acetylacetonate (Mg(acac)2), respectively.
Fourier transform infra-red (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis on the coatings revealed
that Ca2+and Mg2+ ions can be successfully doped into SiOC coating after aging and annealing in the SiCaMgOC
coating. The cytotoxicity and bioactivity of three samples have been detected by MTT assay, cell adhesion and
simulated boy ffuid (SBF) immersion test. The results suggested that SiCaMgOC coating induced more apatite
than that of C/C and SiOC in the comparable soaking process. SiCaMgOC coating demonstrated better biological
activity and cellular adherence for its higher surface roughness and ion exchange reaction between Ca2+and
Mg2+ ions and protons (H+/H3O+) in the SBF solution. Indexed by:Journal paper Discipline:Engineering First-Level Discipline:Materials Science and Engineering Document Type:J Volume:49 Issue:34248–34254 Translation or Not:no Date of Publication:2023-08-12 Included Journals:SCI -
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Bioactivity of SiOC and SiCaMgOC coatings prepared by sol-gel method --陈红梅.pdf
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