Yedi Zhou   

Professional Title:Associate Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates
Main positions:Associate Professor
Other Post:Attending Doctor

Honors and Titles:

2023-04-27    中南大学湘雅二医院“青年岗位能手”

2020-08-19    Top 10 Residents of the Second Xiangya Hospital, Central South University (2020)

2012-09-24    China Scholarship Council State Grant(2012-2016)

2015-02-18    Asia-ARVO Travel Grant Award (2015)

2017-04-03    The 121st Japanese Ophthalmological Society Annual Meeting Travel Grant Award(2017)

2019-04-16    The 123rd Japanese Ophthalmological Society Annual Meeting Travel Grant Award(2019)

MORE> Recommended Ph.D.Supervisor Recommended MA Supervisor
Language: 中文


I am currently working in the field of Ophthalmology at the Second Xiangya Hospital of Central South University, China. I finished my medical degree at Xiangya School of Medicine, Central South University in China, and received my Ph.D. degree from Kyushu University in Japan. My research interest is focusing on the immunological mechanisms of retinal and choroidal neovascular diseases, such as diabetic retinopathy (DR), retinopathy of prematurity (ROP) and age-related macular degeneration (AMD). I have published more than 40 English papers in peer-reviewed journals, and served as reviewers for more than 30 scientific journals including Molecular Therapy, Journal of Neuroinflammation, Experimental Eye Research, Scientific Reports, etc. I am also serve as the Editorial Board Member for BMC Ophthalmology, and Journal of Ophthalmology, and the Associate Editor for Heliyon.

Positions are available international Ph.D students (Major: Ophthalmology) and Postdocs from overseas. 

International students and researchers are welcome to apply! 

Applicants of Ph.D course shall have the bachelor and master degrees of clinical medicine, and obtained a score of 220 or above on HSK 5(汉语水平考试).

Postdoc applicants shall have obtained their doctoral degree within 3 years and aged under 35 years old. 

If you are insterested in joining our research group, please feel free to contact me by E-mail.

Yedi Zhou, M.D., Ph.D. 周 也荻
Associate Professor/Attending Doctor/Ph.D Supervisor
Department of Ophthalmology, The Second Xiangya Hospital, Central South University
Hunan Clinical Research Center of Ophthalmic Disease
Changsha, Hunan 410011, China

ResearchGate Homepage:

List of Recent Publications(2020-2023)


(1) Wang Z, Tan W, Li B, Zou J, Li Y, Xiao Y, He Y, Yoshida S, Zhou Y*. Exosomal non-coding RNAs in angiogenesis: Functions, mechanisms and potential clinical applications. Heliyon. 2023; 9(8): e18626.

(2) Li B#, Tan W#, Wang Z, Zhou H, Zou J, Li Y, Yoshida S, Zhou Y*. Progress and prospects of gene therapy in ophthalmology from 2000 to 2022: A bibliometric analysis. Heliyon. 2023; 9(7): e18228.

(3) Zhou Y, Wang Z, Zhou H, Tan W, Cai Y, Liu J, Huang Q, Li B, He Y, Yoshida S, Li Y*. Identification and clinical significance of tsRNAs and miRNAs in PBMCs of treatment-requiring retinopathy of prematurity. Exp Eye Res. 2023; 109518.

(4) Zhou Y, Li B, Wang Z, Tan W, Zou J, Zhou H, Cai Y, Liu J, He Y, Yoshida S, Li Y*. m6A modifications of circular RNAs in ischemia-induced retinal neovascularization. Int J Med Sci 2023; 20(2):254-261.


(1) Ding C, Wang N, Wang Z, Yue W, Li B, Zeng J, Yoshida S, Yang Y*, Zhou Y*. Integrated Analysis of Metabolomics and Lipidomics in Plasma of T2DM Patients with Diabetic Retinopathy. Pharmaceutics. 2022;14(12):2751.

(2) Zhou Y*, Li S*, Yoshida S*. Editorial: Non-coding RNAs in ophthalmic diseases. Front Genet. 2022;13:1055701.

(3) Li Y, Zhou H, Huang Q, Tan W, Cai Y, Wang Z, Zou J, Li B, Yoshida S, Zhou Y*. Potential biomarkers for retinopathy of prematurity identified by circular RNA profiling in peripheral blood mononuclear cells. Front Immunol. 2022;13:953812.

(4) Yang Y, Yue W, Wang N, Wang Z, Li B, Zeng J, Yoshida S, Ding C*, Zhou Y*. Altered Expressions of Transfer RNA-Derived Small RNAs and microRNAs in the Vitreous Humor of Proliferative Diabetic Retinopathy. Front Endocrinol. 2022;13:913370. 

(5) Zou J, Tan W, Li B, Wang Z, Li Y, Zeng J, Jiang B, Yoshida S, Zhou Y*. Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2022; 63(8):9. 

(6) Peng Y, Wang Z, Li B, Tan W, Zou J, Li Y, Yoshida S, Zhou Y*. N6-methyladenosine modifications of mRNAs and long noncoding RNAs in oxygen-induced retinopathy in mice. Exp Eye Res. 2022; 220:109114. 

(7) Tan W, Li B, Wang Z, Zou J, Jia Y, Yoshida S, Zhou Y*. Novel Potential Biomarkers for Retinopathy of Prematurity. Front Med. 2022; 9:840030.


(1) Zhou Y#, Xu Y#, Zhang X, Huang Q, Tan W, Yang Y, He X, Yoshida S, Zhao P*, Li Y*. Plasma levels of amino acids and derivatives in retinopathy of prematurity. Int J Med Sci. 2021; 18(15):3581-3587.

(2) Li Y, Cai Y, Huang Q, Tan W, Li B, Zhou H, Wang Z, Zou J, Ding C, Jiang B, Yoshida S, Zhou Y*. Altered Fecal Microbiome and Metabolome in a Mouse Model of Choroidal Neovascularization. Front Microbiol. 2021;12:738796.

(3) Li W, Liu J, Tan W, Zhou Y*. The role and mechanisms of Microglia in Neuromyelitis Optica Spectrum Disorders. Int J Med Sci. 2021;18(14):3059-3065.

(4) Zhou Y, Tan W, Zou J, Cao J, Huang Q, Jiang B, Yoshida S, Li Y*. Metabolomics Analyses of Mouse Retinas in Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2021; 62(10):9. 

(5) Li BY, Tan W, Zou JL, He Y, Yoshida S, Jiang B, Zhou YD*. Role of interferons in diabetic retinopathy. World J Diabetes. 2021; 12(7):939-953.

(6) Ren Y#, Dong X#, Zhao H#, Feng J, Chen B, Zhou Y, Peng Y, Zhang L, Zhou Q, Li Y, Wu M, He Y*. Myeloid-derived suppressor cells improve corneal graft survival through suppressing angiogenesis and lymphangiogenesis. Am J Transplant. 2021; 21(2):552-566. 


(1) Jia Y, Tan W, Zhou Y*. Transfer RNA-derived small RNAs: potential applications as novel biomarkers for disease diagnosis and prognosis. Ann Transl Med. 2020; 8(17):1092.

(2) Tan W, Zou J, Yoshida S, Jiang B, Zhou Y*. The Role of Inflammation in Age-Related Macular Degeneration. Int J Biol Sci. 2020; 16(15):2989-3001. 

(3) Tan W, Zou JL, Yoshida S, Jiang B, Zhou YD*. Increased vitreal levels of interleukin-10 in diabetic retinopathy: a Meta-analysis. Int J Ophthalmol. 2020;13(9):1477-1483.

(4) Zhou Y, Xu Y, Zhang X, Zhao P, Gong X, He M, Cao J, Jiang B, Yoshida S, Li Y*. Plasma metabolites in treatment-requiring retinopathy of prematurity: Potential biomarkers identified by metabolomics. Exp Eye Res. 2020; 199: 108198. 

(5) Peng Y, Zou J, Wang JH, Zeng HL, Tan W, Yoshida S, Zhang L, Li Y, Zhou Y*. Small RNA Sequencing Reveals Transfer RNA-derived Small RNA Expression Profiles in Retinal Neovascularization. Int J Med Sci 2020; 17(12):1713-1722.

(6) Jia Y, Zhou Y*. Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis. J Immunol Res. 2020; 2020:1704631. 

(7) Zhang L, Zeng H, Wang JH, Zhao H, Zhang B, Zou J, Yoshida S, Zhou Y*. Altered Long Non-coding RNAs Involved in Immunological Regulation and Associated with Choroidal Neovascularization in Mice. 2020; 17(3):292-301.

(8) Liu X, Zhang L, Wang JH, Zeng H, Zou J, Tan W, Zhao H, He Y, Shi J, Yoshida S, Li Y, Zhou Y*. Investigation of circRNA Expression Profiles and Analysis of circRNA-miRNA-mRNA Networks in an Animal (Mouse) Model of Age-Related Macular Degeneration. Curr Eye Res. 2020; 45(9):1173-1180. 

Educational Background

  • 2013.4-2016.9  

    Kyushu University (Japan)       Ophthalmology       Ph.D       Doctoral degree

  • 2012.10-2013.3  

    Kyushu University (Japan)       Ophthalmology       Research Student       Research Student

  • 2011.9-2012.9  

    Central South University       Ophthalmology       Master student       Master student

  • 2006.9-2011.6  

    Central South University       Clinical Medicine       University graduated       Bachelor's degree

Work Experience

  • 2020.9-Now

    The Second Xiangya Hospital, Central South University      Department of Ophthalmology      Associate Professor

  • 2020.9-Now

    The Second Xiangya Hospital, Central South University      Department of Ophthalmology      Attending Doctor

  • 2016.10-2020.9

    The Second Xiangya Hospital, Central South University      Department of Ophthalmology      Assistant Professor

Research Group

Name of Research Group:

Scientific Research Members

Description of Research Group:

Our research team focus on retinal/choroidal neovascular diseases, cataract and lens diseases, ocular immunology and neuro-ophthalmology.

Name of Research Group:

Graduated Members

Name of Research Group:

Overseas Research Cooperative Partners
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