I am currently working in the field of Ophthalmology at the Second Xiangya Hospital of Central South University, China. I finished my medical degree at Xiangya School of Medicine, Central South University in China, and received my Ph.D. degree from Kyushu University in Japan. My research interest is focusing on the immunological mechanisms of retinal and choroidal neovascular diseases, such as diabetic retinopathy (DR), retinopathy of prematurity (ROP) and age-related macular degeneration (AMD). I have published more than 40 English papers in peer-reviewed journals, and served as reviewers for more than 30 scientific journals including Molecular Therapy, Journal of Neuroinflammation, Experimental Eye Research, Scientific Reports, etc. I am also serve as the Editorial Board Member for BMC Ophthalmology, and Journal of Ophthalmology, and the Associate Editor for Heliyon.

Positions are available international Ph.D students (Major: Ophthalmology) and Postdocs from overseas. 

International students and researchers are welcome to apply! 

Applicants of Ph.D course shall have the bachelor and master degrees of clinical medicine, and obtained a score of 220 or above on HSK 5（汉语水平考试）.

Postdoc applicants shall have obtained their doctoral degree within 3 years and aged under 35 years old. 

If you are insterested in joining our research group, please feel free to contact me by E-mail.

Yedi Zhou, M.D., Ph.D. 周 也荻
Associate Professor/Attending Doctor/Ph.D Supervisor
Department of Ophthalmology, The Second Xiangya Hospital, Central South University
Hunan Clinical Research Center of Ophthalmic Disease
Changsha, Hunan 410011, China
Email: zhouyedi@csu.edu.cn

ResearchGate Homepage: https://www.researchgate.net/profile/Yedi-Zhou

List of Recent Publications（2020-2023）

2024年

(1) Zhou H, Zhang L, Ding C, Zhou Y*, Li Y*. Upregulation of HMOX1 associated with M2 macrophage infiltration and ferroptosis in proliferative diabetic retinopathy. Int Immunopharmacol. 2024; 134: 112231.

(2) Li B^#, Wang Z#, Zhou H, Tan W, Zou J, Li Y, Yoshida S, Zhou Y*. Bibliometric evaluation of global trends and characteristics of RNA methylation during angiogenesis. Heliyon. 2024; 10(8): e29817.

(3) 陈海霞, 周也荻*. 临床医学“专硕+学硕”科研能力培养模式的构建. 卫生职业教育, 2024; 42(6): 4-7（教学论文）

(4) Li B, Wang Z, Zhou H, Zou J, Yoshida S, Zhou Y*. N6-methyladenosine methylation in ophthalmic diseases: From mechanisms to potential applications. Heliyon. 2024; 10(1):e23668.

2023年

(1) Wang Z, Tan W, Li B, Zou J, Li Y, Xiao Y, He Y, Yoshida S, Zhou Y*. Exosomal non-coding RNAs in angiogenesis: Functions, mechanisms and potential clinical applications. Heliyon. 2023; 9(8): e18626.

(2) Li B^#, Tan W^#, Wang Z, Zhou H, Zou J, Li Y, Yoshida S, Zhou Y*. Progress and prospects of gene therapy in ophthalmology from 2000 to 2022: A bibliometric analysis. Heliyon. 2023; 9(7): e18228.

(3) Zhou Y, Wang Z, Zhou H, Tan W, Cai Y, Liu J, Huang Q, Li B, He Y, Yoshida S, Li Y*. Identification and clinical significance of tsRNAs and miRNAs in PBMCs of treatment-requiring retinopathy of prematurity. Exp Eye Res. 2023; 109518.

(4) Zhou Y, Li B, Wang Z, Tan W, Zou J, Zhou H, Cai Y, Liu J, He Y, Yoshida S, Li Y*. m6A modifications of circular RNAs in ischemia-induced retinal neovascularization. Int J Med Sci 2023; 20(2):254-261.

2022年

(1) Ding C, Wang N, Wang Z, Yue W, Li B, Zeng J, Yoshida S, Yang Y*, Zhou Y*. Integrated Analysis of Metabolomics and Lipidomics in Plasma of T2DM Patients with Diabetic Retinopathy. Pharmaceutics. 2022;14(12):2751.

(2) Zhou Y*, Li S*, Yoshida S*. Editorial: Non-coding RNAs in ophthalmic diseases. Front Genet. 2022;13:1055701.

(3) Li Y, Zhou H, Huang Q, Tan W, Cai Y, Wang Z, Zou J, Li B, Yoshida S, Zhou Y*. Potential biomarkers for retinopathy of prematurity identified by circular RNA profiling in peripheral blood mononuclear cells. Front Immunol. 2022;13:953812.

(4) Yang Y, Yue W, Wang N, Wang Z, Li B, Zeng J, Yoshida S, Ding C*, Zhou Y*. Altered Expressions of Transfer RNA-Derived Small RNAs and microRNAs in the Vitreous Humor of Proliferative Diabetic Retinopathy. Front Endocrinol. 2022;13:913370. 

(5) Zou J, Tan W, Li B, Wang Z, Li Y, Zeng J, Jiang B, Yoshida S, Zhou Y*. Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2022; 63(8):9. 

(6) Peng Y, Wang Z, Li B, Tan W, Zou J, Li Y, Yoshida S, Zhou Y*. N6-methyladenosine modifications of mRNAs and long noncoding RNAs in oxygen-induced retinopathy in mice. Exp Eye Res. 2022; 220:109114. 

(7) Tan W, Li B, Wang Z, Zou J, Jia Y, Yoshida S, Zhou Y*. Novel Potential Biomarkers for Retinopathy of Prematurity. Front Med. 2022; 9:840030.

2021年

(1) Zhou Y#, Xu Y#, Zhang X, Huang Q, Tan W, Yang Y, He X, Yoshida S, Zhao P*, Li Y*. Plasma levels of amino acids and derivatives in retinopathy of prematurity. Int J Med Sci. 2021; 18(15):3581-3587.

(2) Li Y, Cai Y, Huang Q, Tan W, Li B, Zhou H, Wang Z, Zou J, Ding C, Jiang B, Yoshida S, Zhou Y*. Altered Fecal Microbiome and Metabolome in a Mouse Model of Choroidal Neovascularization. Front Microbiol. 2021;12:738796.

(3) Li W, Liu J, Tan W, Zhou Y*. The role and mechanisms of Microglia in Neuromyelitis Optica Spectrum Disorders. Int J Med Sci. 2021;18(14):3059-3065.

(4) Zhou Y, Tan W, Zou J, Cao J, Huang Q, Jiang B, Yoshida S, Li Y*. Metabolomics Analyses of Mouse Retinas in Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2021; 62(10):9. 

(5) Li BY, Tan W, Zou JL, He Y, Yoshida S, Jiang B, Zhou YD*. Role of interferons in diabetic retinopathy. World J Diabetes. 2021; 12(7):939-953.

(6) Ren Y#, Dong X#, Zhao H#, Feng J, Chen B, Zhou Y, Peng Y, Zhang L, Zhou Q, Li Y, Wu M, He Y*. Myeloid-derived suppressor cells improve corneal graft survival through suppressing angiogenesis and lymphangiogenesis. Am J Transplant. 2021; 21(2):552-566. 

2020年

(1) Jia Y, Tan W, Zhou Y*. Transfer RNA-derived small RNAs: potential applications as novel biomarkers for disease diagnosis and prognosis. Ann Transl Med. 2020; 8(17):1092.

(2) Tan W, Zou J, Yoshida S, Jiang B, Zhou Y*. The Role of Inflammation in Age-Related Macular Degeneration. Int J Biol Sci. 2020; 16(15):2989-3001. 

(3) Tan W, Zou JL, Yoshida S, Jiang B, Zhou YD*. Increased vitreal levels of interleukin-10 in diabetic retinopathy: a Meta-analysis. Int J Ophthalmol. 2020;13(9):1477-1483.

(4) Zhou Y, Xu Y, Zhang X, Zhao P, Gong X, He M, Cao J, Jiang B, Yoshida S, Li Y*. Plasma metabolites in treatment-requiring retinopathy of prematurity: Potential biomarkers identified by metabolomics. Exp Eye Res. 2020; 199: 108198. 

(5) Peng Y, Zou J, Wang JH, Zeng HL, Tan W, Yoshida S, Zhang L, Li Y, Zhou Y*. Small RNA Sequencing Reveals Transfer RNA-derived Small RNA Expression Profiles in Retinal Neovascularization. Int J Med Sci 2020; 17(12):1713-1722.

(6) Jia Y, Zhou Y*. Involvement of lncRNAs and Macrophages: Potential Regulatory Link to Angiogenesis. J Immunol Res. 2020; 2020:1704631. 

(7) Zhang L, Zeng H, Wang JH, Zhao H, Zhang B, Zou J, Yoshida S, Zhou Y*. Altered Long Non-coding RNAs Involved in Immunological Regulation and Associated with Choroidal Neovascularization in Mice. 2020; 17(3):292-301.

(8) Liu X, Zhang L, Wang JH, Zeng H, Zou J, Tan W, Zhao H, He Y, Shi J, Yoshida S, Li Y, Zhou Y*. Investigation of circRNA Expression Profiles and Analysis of circRNA-miRNA-mRNA Networks in an Animal (Mouse) Model of Age-Related Macular Degeneration. Curr Eye Res. 2020; 45(9):1173-1180.