《Journal of Immunology Research》特刊征稿
发布时间：2020-12-07
点击次数：
《Journal of Immunology Research》（IF：3.327）主要发表与经典免疫学、分子免疫学、临床免疫学、癌症免疫学、移植免疫学、免疫病理学、免疫缺陷、自身免疫疾病、免疫紊乱和免疫治疗等相关的研究成果和进展，为从事免疫学不同领域的科学家和临床医生提供学术发表和交流平台。此次征稿的专刊，旨在探讨炎症反应在衰老过程和年龄相关性疾病中的调控作用和机制，并关注与炎症相关的诊断和治疗方法在这一领域潜在的临床应用。专刊面向全球征稿，投稿提交的截止时间为2021年3月26日，将于2021年8月前正式发表。
客座编委团队：
周也荻（中南大学湘雅二医院）
Sing-Wai Wong（北卡罗来纳大学教堂山分校）
彭伟军（中南大学湘雅二医院）
Ning Cheng（加州大学旧金山分校）
专刊网址：https://www.hindawi.com/journals/jir/si/323724/
Description:
Inflammation is a key feature of aging and is closely associated with multiple age-related diseases, such as neurodegeneration, atherosclerosis, arthritis, cancer, metabolic disorders, periodontitis, and macular degeneration. This heightened inflammatory response, called inflamm-aging, contributes to the molecular changes associated with aging and the pathogenesis of these age-related diseases.
Inflammation is orchestrated by the activity of different types of immune cells, such as lymphocytes, dendritic cells, monocytes/macrophages, neutrophils, and mast cells. Homeostasis between inflammation and suppression is balanced by their robust production of a broad array of inflammatory mediators (such as IL-6, TNF-α, ROS) and cell-mediated cytotoxicity with numerous anti-inflammatory cytokines (like IL-10 and TGF-β). These immune cells and pro-/anti-inflammatory factors play a vital role in the process of inflammation and together constitute a complex regulatory network. In particular, differentiation of regulatory T cells and macrophage polarization may play critical roles in disease pathogenesis. Therefore, further understanding of the mechanisms that shape the immune response is warranted to discover novel therapeutic strategies for the clinical treatment of these age-related diseases.
This Special Issue aims to discuss the inflammatory response and its role in and regulation of the aging process and pathogenesis of age-related diseases. We welcome original articles and review articles focusing on the fundamental mechanisms of inflamm-aging, as well as novel approaches for potential clinical applications in this field.
Potential topics include but are not limited to the following:
1. Innate immune cells in inflamm-aging and age-related diseases
2. Th1/Th2/Th17/Treg responses and cytokines in inflamm-aging and age-related diseases
3. Crosstalk among immune cells, non-immune cells, and cytokines, and tissue-specific interactions in aging and age-related diseases
4. Regulation of inflamm-aging by microbiota interactions and dysbiosis in age-related diseases
5. Potential diagnostic and prognostic biomarkers related to inflammation in age-related diseases
6. Novel findings of molecular regulation in the inflammatory response of age-related diseases
7. Novel approaches for anti-inflammation in age-related diseases