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李乾斌
— 博士生导师
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教师姓名：李乾斌
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职称：教授
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职务：博士生导师
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教师拼音名称：liqianbin
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所在单位：湘雅药学院
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学历：博士研究生毕业
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入职时间：2010-04-22
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学位：博士学位
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毕业院校：山东大学
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在职信息：在职
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学科：药学
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招生学科：药学
- Li Q., Fang H., Wang X., Hu G., Wang Q., Xu W. Novel potent 2,5-pyrrolidinedione peptidomimetics as aminopeptidase N inhibitors. Design, synthesis and activity evaluation. Bioorg Med Chem Lett, 2012, 22(2): 850-853.
- Lv M., Chen Z., Hu G., Li Q. Therapeutic strategies of diabetic nephropathy: recent progress and future perspectives. Drug Discov Today, 2015, 20(3): 332-346.
- Yu Z., Ye S., Hu G., Lv M., Tu Z., Zhou K., Li Q. The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy. Future Med. Chem., 2015, 7(3): 269-289.
- Hu L., Wang Z., Yi R., Yi H., Xiao S., Chen Z., Hu G., Li Q. Soluble Guanylate Cyclase: A New Therapeutic Target for Fibrotic Diseases. Curr Med Chem, 2017, 24(29): 3203-3215.
- Ai J., Lv M., Li X., Chen Z., Hu G., Li Q. Synthesis, anti-lung cancer activity and molecular docking study of 3-methylene-2-oxoindoline-5-carboxamide derivatives. Medicinal Chemistry Research, 2018, 27(1): 161-170.
- Xiao S., Li Q., Hu L., Yu Z., Yang J., Chang Q., Chen Z., Hu G. Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go? Mini Rev Med Chem, 2019, 19(18): 1544-1557.
- Yu Z., Chen Z., Su Q., Ye S., Yuan H., Kuai M., Lv M., Tu Z., Yang X., Liu R., Hu G., Li Q. Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives. Bioorg Med Chem, 2019, 27(6): 944-954.
- Zheng B., Peng Y., Wu W., Ma J., Zhang Y., Guo Y., Sun S., Chen Z., Li Q., Hu G. Synthesis and structure-activity relationships of pyrazolo-[3,4-b]pyridine derivatives as adenosine 5'-monophosphate-activated protein kinase activators. Arch Pharm (Weinheim), 2019, 352(8): e1900066.
- Chang Q., Long J., Hu L., Chen Z., Li Q., Hu G. Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents. Bioorg Med Chem, 2020, 28(9): 115404.
- Hu L., Li L., Chang Q., Fu S., Qin J., Chen Z., Li X., Liu Q., Hu G., Li Q. Discovery of Novel Pyrazolo[3,4-b] Pyridine Derivatives with Dual Activities of Vascular Remodeling Inhibition and Vasodilation for the Treatment of Pulmonary Arterial Hypertension. J Med Chem, 2020, 63(19): 11215-11234.
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中南大学
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