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Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

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School/Department:Pharmaceutical Sciences

Administrative Position:Professor

Business Address:长沙市岳麓区桐梓坡路172号湘雅医学院后栋449

Contact Information:+8613974880914

Alma Mater:Central South University

Discipline:Pharmaceutical Science
Chemistry
Computer Science and Technology

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Research Group

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Dongsheng Cao

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Alma Mater:Central South University

Profile

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Computational Biology and Drug Design (CBDD) Group develops and implements new concepts, algorithms and software for rapid identification of bioactive compounds and pharmaceutical lead structures, and rapid diagnosis and evaluation of complex disease systems. The molecular design cycle involves multiple scientific disciplines and requires rigorous trans-disciplinary thinking. We employ a broad repertoire of machine-learning methods and bio/cheminformatics techniques for automated hypothesis generation, activity prediction and validation. The disease diagnosis aims at studying the relationship between disease phenotype and various omics (genomics, transcriptomics, proteomics, metabolomics, and phenomics), and involves the integration analysis of multi-level omics. We employ a broad repertoire of artificial intelligent methods and bioinformatics/systems biology techniques for automated hypothesis generation, disease diagnosis and biomarker discovery.
1: The development and application of new artificial intelligent and machine learning algorithms in drug discovery
2: Artificial intelligent-based and systems pharmacology-based computer-assisted molecular design
3: Large-scale computational study of the relationship between phenomics and genomics in complex disease systems
4: The development of software, web service and database in systems biology and drug discovery

  • Educational Background
  • Work Experience

[1]  2009.9 to 2013.5
中南大学  | 博士  | PhD Graduate
[2]  2006.9 to 2009.5
中南大学  | 硕士  | With Certificate of Graduation for Study as Master's Candidates
[3]  2002.9 to 2006.6
中南大学  | 学士  | University graduated

[1]   2015.4  to  2017.3
香港浸会大学  | 中医药学院  | 香江学者
[2]   2014.5 to  Now
中南大学  | 湘雅药学院  | 教授

Social Affiliations

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[1]   中南大学临床药学转化与研究中心副主任

[2]   湖南省生物医学信息委员会副主任委员

[3]   中国毒理学会计算毒理学会委员

[4]   Chemometr. Intell. Lab.编委

[5]   CMES-Comp. Model. Eng.副主编