Organocatalytic domino sequence to asymmetrically access spirocyclic oxindole-α-methylene-γ-lactams
发布时间:2021-07-02
点击次数:
发表刊物:Tetrahedron
摘要:An asymmetric allylic alkylation-lactamization domino sequence of 3-aminooxindoles with Morita-Baylis-Hillman carbonates catalyzed by quinidine derivative (β-ICD) was developed. And a series of chiral spirocyclic oxindole-α-methylene-γ-lactams have been facilely prepared in good yields and stereoselectivities. This developed protocol would broaden the utilization of Morita-Baylis-Hillman carbonates in asymmetric construction of spirocyclic oxindoles.
合写作者:Yu Zheng, Yu-Lun Qian
第一作者:Zhen-Zhen Xie
论文类型:期刊论文
通讯作者:Kai Chen*, Hua Yang*
学科门类:理学
一级学科:化学
卷号:89
页面范围:132163
是否译文:否
发表时间:2021-06-04
收录刊物:SCI