刘元东

副教授 硕士生导师

入职时间:2009-03-12

所在单位:资源加工与生物工程学院

学历:博士研究生毕业

性别:男

学位:博士学位

在职信息:在职

毕业院校:中南大学

学科:生物学
矿业工程
化学
环境科学与工程
计算机科学与技术

个人简介

 

刘元东,湖南邵阳人,博士,教育部和科技部评审专家、湖南省和广东省科技评审专家、长沙市科技评审专家,国际生物湿法冶金学会秘书、院士秘书、Frontiers in Bioscience-LandmarkFrontiers in Bioleaching等国际杂志审稿人。主持或参与国家级省部级等项目10多项,发表SCI论文60多篇,获得专利30多项,获得软件著作权20多项,获得省级等奖励荣誉3项。

 

联系方式:

邮箱:yuandong_liu@csu.edu.cn

QQ: 438320825

电话:0731-88877472

地址:湖南省长沙市岳麓区麓山南路932中南大学生物楼

 

工作教育经历:

2009-至今,中南大学,资源加工与生物工程,教学科研

2016-2018,美国加州大学,访问学者,结构生物学与生物传感器应用研究

2004-2008,中南大学,生物工程,博士

2001-2004,中南大学,材料学,硕士

1997-2001,中南工业大学,无机非金属材料专业,本科

 

研究方向:

1)蛋白质功能结构解析

2)生物传感与环境监测

3)生物冶金与极端环境微生物

4)微生物组学、生物信息学与软件开发

5)矿物资源处理及其污染治理

 

科研项目:

1)新颖银离子陷阱蛋白的分子作用机制及其荧光生物传感器应用基础,长沙市自然科学基金,主持

2)生物浸矿过程微生物的高密度培育,国家自然科学基金面上项目,主持

3)冶金微生物信息学高通量大数据云计算平台的研制,湖南省自然科学基金面上项目,主持

4)嗜酸氧化亚铁硫杆菌浸矿过程胞外多糖的形成、组成与功能研究,湖南省自然科学基金面上项目,主持

5)基于生物信息学的嗜酸氧化亚铁硫杆菌浸矿过程能量传递体系的研究,国家自然科学基金项目,主持

6)外加碳氮氧源强化生物浸矿铁硫氧化过程研究,中国博士后科学基金特别资助项目,主持

7)生物浸矿过程微生物群落铁硫氧化机理研究,中国博士后科学基金面上项目,主持

8)嗜酸氧化亚铁硫杆菌全基因组序列的生物信息学挖掘及比较,中南大学引进人才基金项目,主持

9 微生物冶金过程强化的基础研究,国家重大基础研究项目,参与

10)微生物冶金的基础研究,国家重大基础研究,参与

11)硫化矿生物提取的基础研究,国家自然科学基金创新群体项目,参与

 

 

学术论文:

1Yuandong Liu, Shuhui Guo, Runlan Yu, Guanzhou Qiu. A New Cytoplasmic Monoheme Cytochrome c from Acidithiobacillus ferrooxidans Involved in Sulfur Oxidation.Current Microbiology, 70(1), 2013/10/16.

2Yuandong Liu, Shuhui Guo, Runlan Yu, Jiaju Ji, Guanzhou Qiu. HdrC2 from Acidithiobacillus ferrooxidans Owns Two Iron-Sulfur Binding Motifs But Binds Only One Variable Cluster Between [4Fe-4S]and [3Fe-4S]Current Microbiology, 66(1), pp 88-95, 20130.

3Yuandong Liu, Jiaju Ji, Runlan Yu, Guanzhou Qiu. Expression, Purification and Molecular Modeling of Another HdrC from Acidithiobacillus ferrooxidans Which Binds Only One [4Fe-4S] ClusterCurrent Microbiology, 65(4), pp 416-423, 2012/101.

4LIU Yuan-dong, QIU Guan-zhou, WANG Hai-dong, JIANG Ying, ZHANG Cheng-gui, XIA Le-xian. Full structurebuilding and docking of NifS from extremophile Acidithiobacillus ferrooxidansTransactions of Nonferrous Metals Society of China, 18(4), pp 995-1002, 2008/80.

5LIU Yuan-dong, WANG Hai-dong, QIU Guan-zhou. Homology modeling and evolutionary trace analysis of superoxide dismutase from extremophile Acidithiobacillus ferrooxidansJournal of Central South University of Technology, 14(5), pp 612-617, 2007/10 .

6LIU Yuan-dong, DING Jian-nan, QIU Guan-zhou*, WANG Hai-dong. Homology modeling and docking studies of IscS from extremophile Acidithiobacillus ferrooxidans Journal of Central South University of Technology, 14(6), pp 742-749, 2007/12 1 .

7Liu Yuan-dong; Gao Jian; Qiu Guan-zhou; Liu Xue-duan; Zhang Cheng-gui; Ouyang Xu-dong; Jiang Ying; Zeng Jia. Expression, purification and molecular modeling of iron-containing superoxide dismutase from Acidithiobacillus ferrooxidansTransactions of Nonferrous Metals Society of China, 2008/12.

8Yuandong Liu, Xuan Yi, Wenqing Qin, Guanzhou Qiu. Expression, purification, mutation and bioinformatics analysis of a ferredoxin containing [2Fe-2S] cluster from Leptospirillum ferrooxidansProtein Expression and Purification, 2014.

9Yuandong Liu, Shuhui Guo, Runlan Yu, Guanzhou Qiu. Differential Gene Expression and Bioinformatics Analysis of cyoA Gene in Acidithiobacillus ferrooxidansBiotechnology Letters,, 2014 .

10Yuandong Liu, Guanzhou Qiu, Jiaju Ji, Wenqing Qin, Kai Zou, Yaoyao Bi. Investigating the effect of limestone on bioleaching of a chalcopyrite concentrate by Acidithiobacillus ferrooxidans 20th International Biohydrometallurgy Symposium (IBS2013), 2013/10/

11Shuhui Guo, Xiaohong Ma, Huina Qin, Guanzhou Qiu, Yuandong Liu*. Reduced inorganic sulfur compounds oxidation model of Acidithiobacillus ferrooxidans 20th International Biohydrometallurgy Symposium (IBS2013), 2013/10/8-2013/10/11, p 129, Antofagasta,

12Yuandong Liu; Guanzhou Qiu. Structure prediction and docking study of RpiA from extremophile Acidithiobacillus ferrooxidan19th International Biohydrometallurgy Symposium IBS2011,2011/9/18-2011/9/22, pp 393-399, Changsha, 2011/9/18 会议论文

13Zeng, Jia; Liu, Yuandong; Wu, Long; Li, Ding. Mutation of Tyr375 to Lys375 allows medium-chain acyl-CoA dehydrogenase to acquire acyl-CoA oxidase activity Biochimica et Biophysica Acta-Proteins and Proteomics, 1774(12), pp 1628-1634, 2007/12 4

14Qi Hu; Xueling Wu; Ying Jiang; Yuandong Liu; Yili Liang; Xueduan Liu; Huaqun Yin; Ngom Baba. Differential Gene Expression and Bioinformatics Analysis of Copper Resistance Gene afe_1073 in Acidithiobacillus ferrooxidans Biological Trace Element Research, 151(1), 2013/1/24

15Zeng, Jia; Wu, Long; Zhang, Xiaojian; Liu, Yuandong; Deng, Guisheng; Li, Ding. Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase Organic Letters, 10(19), pp 4287-4290, 2008/10/2

16Zeng, Jia; Zhang, Yanfei; Liu, Yuandong; Zhang, Xiaojian; Xia, Leixian; Liu, Jianshe; Qiu, Guanzhou. Expression, purification and characterization of a cysteine desulfurase, IscS, from Acidithiobacillus ferrooxidans Biotechnology Letters, 29(12), pp 1983-1990, 2007/12 3

17Luo, Yanjie; Liu, Yuandong; Zhang, Chenggui; Luo, Hailang; Guan, Hao; Liao, Hehuan; Qiu, Guanzhou; Liu, Xueduan. Insights into two high homogenous genes involved in copper homeostasis in Acidithiobacillus ferrooxidans Current Microbiology, 57(4), pp 274-280, 2008/10 6

18Zeng, Jia; Geng, Meimei; Liu, Yuandong; Xia, Lexian; Liu, Jianshe; Qiu, Guanzhou. The sulfhydryl group of Cys 138 of rusticyanin from Acidithiobacillus ferrooxidans is crucial for copper binding Biochimica et Biophysica Acta-Proteins and Proteomics, 1774(4), pp 519-525, 2007/4 7

19Zeng, Jia; Zhao, Wenjie; Liu, Yuandong; Xia, Lexian; Liu, Jianshe; Qiu, Guanzhou. Expression,purification and characterization of an iron-sulfur cluster assembly protein, IscU, from Acidithiobacillus ferrooxidans Biotechnology Letters, 29(12), pp 1965-1972, 2007/12 4

20Ai, Chenbing; Mo, Hongyu; Chen, Qian; Liu, Yuandong; Tang, Lin; Du, Juan; *Zeng, Jia. Expression,Purification, and Characterization of an Iron Chaperon Protein CyaY from Acidithiobacillus ferrooxidansCurrent Microbiology, 62(3), pp 733-738, 2011/3 1

21Zeng Jia; Liu, Qing; Zhang, Xiaojian; Mo, Hongyu; Wang, Yiping; Chen, Qian; Liu, Yuandong. Functional Roles of the Aromatic Residues in the Stabilization of the [Fe4S4] Cluster in the Iro Protein from Acidithiobacillus ferrooxidans Journal of Microbiology and Biotechnology, 20(2), pp 294-300, 2010/20

22Zhang, Cheng-gui; Xia, Jin-lan; Liu, Yuan-dong; He, Huan; Qiu, Guan-zhou. The putative thiol-disulphide interchange protein DsbG from Acidithiobacillus ferrooxidans has disulphide isomerase activityScienceAsia, 36(2), pp 100-104, 2010/6 0 SCI 期刊论文

 

 

获奖荣誉:

[1] 中度高温环境下冶金微生物菌种选育及其硫化矿浸出机理,湖南省科学技术奖励工作办公室,2014年度湖南省自然科学奖( 二等奖 )2014

[2]《应用驱动的生物信息学教学创新》-教育基础课程改革教研成果,中国教育发展学会,2013