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李明，教授，博士，材料物理系 中南大学材料科学与工程学院教授，国家“四青”人才， 博士生导师 课题组主页： https://ming-group.com/ Group Website: https://ming-group.com/ https://orcid.org/0000-0002-2289-0222 ------------------------------------------
博士毕业于美国西弗吉尼亚大学 硕士毕业于浙江大学材料科学与工程学院 本科毕业于大连理工大学精细化工系 先后在美国圣母大学、麻省理工学院和约翰霍普金斯大学从事博士后研究工作。
研究方向： 主要从事新型生物医用材料、生物传感器和体外检测等方面的基础研究和应用研究，在新型表面等离激元材料研制及表面等离激元学、用于体外检测的生物传感技术开发、以及高分辨共聚焦拉曼显微学等方面做了长期系统性研究。曾获得国家优秀自费留学生奖（2011）和美国激光医学和手术协会fellowship（2015）等多项奖。近年来，课题组在Science Advances、Nature Communications、Advanced Materials、Angewandte Chemie International Edition、ACS Nano、Advanced Functional Materials、Nano Letters、Coordination Chemistry Reviews、Chemical Engineering Journal、Small、Chemistry of Materials、Analytical Chemistry、Biosensors and Bioelectronics、ACS Sensors等主流学术期刊发表学术论文80余篇，SCI引用次数12000余次。 主要从事以下几个方面的研究： 1、新型生物医用材料； 2、生物传感器和医学体外检测，侧重于癌症等重大疾病的早期诊断检测； 3、可穿戴式生物传感器和医疗器械。 联系方式：liming0823 at csu.edu.cn 或liming0823 at gmail.com(at 用 @ 替代）。
课程讲授 1.《生物材料》每年秋冬学期，64学时4学分，材料科学与工程学院材料国际专业和材料学院卓越班 2. 《生物医用材料及生物传感》每年秋冬学期，72学时，湘雅附二临床医学（五年制）卓越医生班
代表性论文 （https://scholar.google.com/citations?hl=en&user=m5IrnO8AAAAJ&view_op=list_works&sortby=pubdate） 2024
Molecular-Sieving Label-Free Surface-Enhanced Raman Spectroscopy for Sensitive Detection of Trace Small-Molecule Biomarkers in Clinical Samples Nano Letters 2024, DOI: 10.1021/acs.nanolett.4c02890
SERS Surgical Navigation with Postsurgical Immunotherapy of Local Microtumors and Distant Metastases for Improved Anticancer Outcomes Science Advances 2024, 10, eado2741
An Intramolecular Rotor-Bridged Dimeric Cyanine Photothermal Transducer for Efficient Near-Infrared II Fluorescence Imaging-Guided Mitochondria-Targeted Phototherapy ACS Sensors 2024, 9(7), 3581–3593
Targeted SERS Imaging and Intraoperative Real-Time Elimination of Microscopic Tumors for Improved Breast-Conserving Surgery Advanced Materials 2024, 36(32), 2405253
An Active Self-Mitochondria-Targeting Cyanine Immunomodulator for Near-Infrared II Fluorescence Imaging-Guided Synergistic Photodynamic Immunotherapy Advanced Healthcare Materials 2024, DOI: 10.1002/adhm.202401061
Sterically Twisted Mitochondria-Targeting Photosensitizers for Augmented Near-Infrared II Fluorescence-Guided Photodynamic Immunotherapy Advanced Functional Materials 2024, DOI: 10.1002/adfm.202402663
Chien-hong Lin, Hong Zhong, Ming Li* SERS lateral flow strip detection of serum biomarkers for noninvasive assessment of operative microwave ablation outcomes of unresectable hepatocellular carcinoma Chemical Engineering Journal 2024, 485, 149833
Rational Design of Near‐infrared II Plasmonic Optofunctional Materials for Diagnostic and Therapeutic Applications Advanced Functional Materials 2024, 38(18), 2312753
Self-calibrating surface-enhanced Raman scattering-lateral flow immunoassay for determination of amyloid-β biomarker of Alzheimer's disease Biosensors and Bioelectronics 2024, 245, 115840
Engineering Near-Infrared Plasmonic Spiky Gold Nanostructures for Highly Efficient Surface-Enhanced Raman Spectroscopy-Guided Cancer Hyperthermia Therapy Advanced Functional Materials 2024, 34(1), 2307631
2023
Biomimetic Construction of Degradable DNAzyme-Loaded Nanocapsules for Self-Sufficient Gene Therapy of Pulmonary Metastatic Breast Cancer ACS Nano2023, 17(21), 22129–22144
Artificial Intelligence-Assisted Label-Free Spectroscopic Quantification of Global DNA Cytosine Methylation in a Miniature Plasmonic Pickering Emulsion Advanced Functional Materials 2023, 33(48), 2307091.
Absolute Quantification of Serum Exosomes in Patients with an SERS-Lateral Flow Strip Biosensor for Noninvasive Clinical Cancer Diagnosis ACS Applied Materials & Interfaces 2023, 15(31), 37130–37142.
Symmetry-Breaking Effects of Near-Infrared II Thermoplasmonics of Gold–Silica–Cuprous Selenide Hybrid Nanoshells Journal of Physical Chemistry C 2023, 127(22), 10757–10765.
Quantitative Analysis of the Shape Effect of Thermoplasmonics in Gold Nanostructures Journal of Physical Chemistry Letters 2023, 14 (16), 3853-3860.
Apex-Confined Plasmonic Tip for High Resolution Tip-Enhanced Raman Spectroscopic Imaging of Carbon Nanotubes ACS Applied Materials & Interfaces, 2023, 15(13), 16984–16990.
Integrated SERS-Vertical Flow Biosensor Enabling Multiplexed Quantitative Profiling of Serological Exosomal Proteins in Patients for Accurate Breast Cancer Subtyping ACS Nano 2023, 17(1), 4077-4088.
Quantitative Label-Free SERS Detection of Trace Fentanyl in Biofluids with a Freestanding Hydrophobic Plasmonic Paper Biosensors Analytical Chemistry 2023, 95(7), 3821–3829.
Additional Important Considerations in Surface-Enhanced Raman Scattering Enhancement Factor Measurements Journal of Physical Chemistry C 2023, 127(5), 2728-2734. 2022
Artificial intelligent label-free SERS profiling of serum exosomes for breast cancer diagnosis and postoperative assessment Nano Letters 2022, 22(19), 7910–7918.
Near-infrared II plasmonic porous cubic nanoshells for in vivo noninvasive SERS visualization of sub-millimeter microtumors Nature Communications 2022, 13, 5249.
Label-free plasmon-enhanced spectroscopic HER2 detection for dynamic therapeutic surveillance of breast cancer Analytical Chemistry 2022, 94(37), 12762–12771.
Biodegradable copper telluride nanosheets for redox-homeostasis breaking-assisted chemodynamic cancer therapy boosted by mild-photothermal effect Chemical Engineering Journal 2022, 450, 138348
Biodegradable Amorphous Copper Iron Tellurite Promoting the Utilization of Fenton-like Ions for Efficient Synergistic Cancer Theranostics ACS Applied Materials & Interfaces 2022, 14 (25), 28537-28547
Structural symmetry effects in plasmonic metal-semiconductor hybrid heterostructures for multimodal cancer phototheranostics Chemical Engineering Journal 2022, 444, 136707.
Near‐infrared II plasmonic tri‐enzyme integrated metal‐organic frameworks with high‐efficiency enzyme cascades for synergistic tri‐modal oncotherapy Advanced Materials 2022, 34(24), 2200871.
Near-infrared II plasmonic phototheranostics with glutathione depletion for multimodal imaging-guided hypoxia-tolerant chemodynamic-photocatalytic-photothermal cancer therapy triggered by a single laser Small 2022, 18(4), 2105638. 2021
Degradable carrier-free metal−phenolic network theranostic agent with targeted mitochondrial damage for efficient cancer theranostics Chemistry of Materials 2021, 33(17), 7089-7099.
Role of trap states in excitation wavelength-dependent photoluminescence of strongly quantum-confined all-inorganic CsPbBr3 perovskites with varying dimensionalities Journal of Physical Chemistry C 2021, 125(38), 21062–21069.
Emerging biosensing platforms for quantitative detection of exosomes as diagnostic biomarkers Coordination Chemistry Reviews 2021, 446, 214111
Leonardo de S Menezes, Emiliano Cortés, Isobel C Bicket, Haiyu Wang, Ning Li, Zhenglong Zhang, Ming Li, Wei Xie, Yifu Yu, Yurui Fang, Shunping Zhang, Hongxing Xu, Alberto Vomiero, Yongchang Liu, Gianluigi A Botton, Stefan A Maier, Hongyan Liang Self-Constructed Multiple Plasmonic Hotspots on an Individual Fractal to Amplify Broadband Hot Electron Generation ACS Nano2021, 15(6), 10553–10564.
Seed shape-controlled, facet-selective growth of superspiky gold nanocrystals for biosensing applications. Journal of Materials Chemistry C 2021, 9, 8694-8704.
Near-infrared II plasmonic Au@Au-Ag dot-in-cubic nanoframes for in vivo surface-enhanced Raman spectroscopic detection and photoacoustic imaging. Advanced Functional Materials 2021, 31(29), 2103186.
Near-Infrared II thermoplasmonics of cuprous selenide multilayer nanoshells: the role of the plasmonic core. Journal of Physical Chemistry Letters 2021, 12, 4928-4935.
Real-time intraoperative surface-enhanced Raman spectroscopy-guided thermosurgical eradication of residual microtumors in orthotopic breast cancer Nano Letters 2021, 21(7), 3066–3074.
A scalable broadband plasmonic cuprous telluride nanowire-based hybrid photothermal membrane for efficient solar vapor generation Nano Energy 2021, 84, 105868. 2020
Rationally designed dual-plasmonic gold nanorod@cuprous selenide hybrid heterostructures by regioselective overgrowth for in vivo photothermal tumor ablation in the second near-infrared biowindow Theranostics 2020, 10(25), 11656-11672.
Molecular hot spots in surface-enhanced Raman scattering Nanoscale 2020, 12, 22036–22041.
A fluorescent and surface-enhanced Raman spectroscopic dual-modal aptasensor for sensitive detection of cyanotoxins ACS Sensors 2020, 5(5), 1419-1426.
Additive-Free Green Light-Induced Ligation Using BODIPY Triggers Angewandte Chemie International Edition 2020, 59, 2284 –2288. 2019
High-Quality Dual-Plasmonic Au@Cu2-xSe Nanocrescents with Precise Cu2-xSe Domain Size Control and Tunable Optical Properties in the Second Near-Infrared Biowindow Chemistry of Materials 2019, 31, 9875-9886.
Yingfan Chen, Ming Li* A graphene oxide-gold nanostar hybrid based-paper biosensor for label-free SERS detection of serum bilirubin for diagnosis of jaundice Biosensors and Bioelectronics, 2019, 145, 111713.
Ultrasensitive Detection of Hepatotoxic Microcystin Production from Cyanobacteria Using Surface-Enhanced Raman Scattering Immunosensor ACS Sensors, 2019, 4, 1203-1210.
In Situ Raman Spectroscopic Studies of Thermal Stability of All-Inorganic Cesium Lead Halide (CsPbX3, X = Cl, Br, I) Perovskite Nanocrystals Journal of Physical Chemistry Letters 2019, 10 (6), 1217–1225. 2017,2018
Novel SERS Labels: Rational Design, Functional Integration and Biomedical Applications Coordination Chemistry Reviews 2018, 371, 11-37.
Jayson V. Pagaduan, Ishan Barman, David H. Gracias Mechanical Trap Surface‐Enhanced Raman Spectroscopy for Three‐Dimensional Surface Molecular Imaging of Single Live Cells Angewandte Chemie International Edition 2017, 56, 3822-3826. Before 2016
Ultrahigh Affinity Raman Probe for Targeted Live Cell Imaging of Prostate Cancer Chemical Science, 2016, 7, 6779-6785.
Multiplexed Detection of Serological Cancer Markers with Plasmon-Enhanced Raman Spectro-immunoassay Chemical Science, 2015, 6, 3906-3914.
Shedding Light on the Extinction-Enhancement Duality in Gold Nanostar-Enhanced Raman Spectroscopy Angewandte Chemie International Edition, 2014, 53, 14115-14119.
Origin of Strong Excitation Wavelength Dependent Fluorescence of Graphene Oxide ACS Nano, 2014, 8, 1002-1013.
Dongling Ma, Yuxin Liu, and Nianqiang Wu Three-Dimensional Hierarchical Plasmonic Nano-architecture Enhanced Surface-Enhanced Raman Scattering Immuno-Sensor for Cancer Biomarker Detection in Blood Plasma ACS Nano, 2013, 7, 4967-4976.
Plasmonic Silver Nanorice Antenna on Gold Triangle Nano-array for Surface-Enhanced Raman Scattering Detection of Hepatitis B Virus DNA Analytical Chemistry, 2013, 85, 2072-2078.
Detection of Lead (II) with a “Turn-On” Fluorescent Sensor Based on Energy Transfer from CdSe/ZnS Quantum Dots to Graphene Oxide Biosensors & Bioelectronics, 2013, 43, 69-74.
Fluorescent Aptamer-Functionalized Graphene Oxide for Label-Free Detection of Mercury (II) Biosensors & Bioelectronics, 2013, 41, 889-893.
Fingerprinting Photoluminescence of Functional Groups in Graphene Oxide Journal of Materials Chemistry, 2012, 22, 23374-23379.
Detection of Mercury (II) by Quantum dot-DNA-Gold Nanoparticle Ensemble Based Nanosensor via Nanometal Surface Energy Transfer Analytical Chemistry, 2011, 83, 7061-7065.
Size-dependent Energy Transfer between CdSe/ZnS Quantum Dots and Gold Nanoparticle Journal of Physical Chemistry Letters, 2011, 2, 2125-2129.
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