Abnormal histone acetylation and methylation levels in esophageal squamous cell carcinomas
发布时间:2016-04-25
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发表刊物:Cancer investigation
摘要:To investigate whether alterations in histone modifications occur in esophageal squamous cell carcinoma (ESCC), we measured histone H3/ H4 acetylation and H3K4/H3K27 methylation levels, as well as the expression of chromatin modifier genes in tumor and healthy esophageal tissue from ESCC patients.Our results suggest that aberrant histone modifications may play an important role in the development and progression of ESCC.
合写作者:Q., B.; Lu, J.; Yin, F.; Hu, Y.; Yu, B.; Yuan, B.; Wang, N.; He, M.; Yin, C.; Zhao, Chen
论文类型:应用研究
学科门类:临床医学
文献类型:J
期号:2011, 29 (8),
页面范围:548-56.
是否译文:否