Inhibiting CD164 expression in colon cancer cell line HCT116 leads to reduced cancer cell proliferation, mobility, and metastasis in vitro and in vivo
发布时间：2016-04-25
点击次数：
发表刊物：Cancer investigation
摘要：BACKGROUND: CD164 (Endolyn) is a sialomucin, which has been found to play roles in regulating proliferation, adhesion, and differentiation of hematopoietic stem cells. Possible association of CD164 with solid cancer development remains unknown.
备注：CONCLUSIONS: CD164 is highly expressed in the colon cancer sites, and it promotes HCT116 colon cancer cell proliferation and metastasis both in vitro and in vivo, and the effects may act through regulating CXCR4 signaling pathway. Therefore, CD164 may be a new target for diagnosis and treatment for colon cancer.
合写作者：G., J.; Li, F.; Xiang, G.; Yu, X.; Zhou, L.; She, J.; Zhang, Tang
论文类型：基础研究
学科门类：临床医学
文献类型：J
期号：2012, 30 (5),
页面范围：380-9
是否译文：否