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李乾斌
— 博士生导师
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教师姓名:李乾斌
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职称:教授
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职务:博士生导师
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教师拼音名称:liqianbin
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所在单位:湘雅药学院
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学历:博士研究生毕业
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入职时间:2010-04-22
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学位:博士学位
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毕业院校:山东大学
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在职信息:在职
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学科:药学
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招生学科:药学
- He Y., Le X., Hu G., Li Q., Chen Z. Discovery of Ureido-Based Apcin Analogues as Cdc20-specific Inhibitors against Cancer. Pharmaceuticals (Basel), 2023, 16(2).
- Hu L., Sun C., Kidd J.M., Han J., Fang X., Li H., Liu Q., May A.E., Li Q., Zhou L., Liu Q. A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi. Nat Commun, 2023, 14(1): 2745.
- Li H., Hu L., Cuffee C.W., Mohamed M., Li Q., Liu Q., Zhou L., Liu Q. Correction: Interdomain interactions dictate the function of the Candida albicans Hsp110 protein Msi3. J. Biol. Chem., 2023, 299(2): 102879.
- Liu R., Chen Z., Hu G., Yu Z., Li Q., Liu D., Li L., Liu Z. A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer. Pharmaceuticals (Basel), 2023, 16(2).
- Ma B., Cao Y., Qin J., Chen Z., Hu G., Li Q. Pulmonary artery smooth muscle cell phenotypic switching: A key event in the early stage of pulmonary artery hypertension. Drug Discov Today, 2023, 28(5): 103559.
- Qin J., Cao M., Hu X., Tan W., Ma B., Cao Y., Chen Z., Li Q., Hu G. Dual inhibitors of ASK1 and PDK1 kinases: Design, synthesis, molecular docking and mechanism studies of N-benzyl pyridine-2-one containing derivatives as anti-fibrotic agents. Eur J Med Chem, 2023, 247: 115057.
- Wu S., Xiao Z., Wei J., Zhang L., Cao Y., Chen Z., Li Q., Hu G. Imidazo[1,2-a]pyridine Derivatives as AMPK Activators: Synthesis, Structure-Activity Relationships, and Regulation of Reactive Oxygen Species in Renal Fibroblasts. ChemMedChem, 2023, 18(8): e202200696.
- Zhao C., Le X., Li M., Hu Y., Li X., Chen Z., Hu G., Hu L., Li Q. Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model. Respir. Res., 2023, 24(1): 289.
- Chen Q., Le X., Li Q., Liu S., Chen Z. Exploration of inhibitors targeting KIF18A with ploidy-specific lethality. Drug Discov Today, 2024, 29(10): 104142.
- Hu X., Wu Y., Ouyang H., Wu J., Yao M., Chen Z., Li Q. Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts. Pharmaceuticals (Basel), 2024, 17(11): 1420.