中南大学李乾斌

Central South University|

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个人信息

李乾斌

教授

教授博士生导师

入职时间：2010-04-22

所在单位：湘雅药学院

职务：博士生导师

学历：博士研究生毕业

办公地点：湖南省长沙市岳麓区桐梓坡路172号中南大学湘雅药学院

在职信息：在职

同专业博导

同专业硕导

论文成果

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Yu, Z., Ye, S., Hu, G., Lv, M., Tu, Z., Zhou, K., Li, Q. The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy. Future Med. Chem. 2015, 7(3): 269-289.
Yu, Z., Wang, Z., Wu, X., Hu, G., Li, Q. "One-Pot" Synthesis of 1-Phenyl-1H-benzimidazole Derivatives Facilitated by Fe. Chin. J. Org. Chem. 2016, 36(7): 1672-1676.
Hu, L., Wang, Z., Yi, R., Yi, H., Xiao, S., Chen, Z., Hu, G., Li, Q. Soluble Guanylate Cyclase: A New Therapeutic Target for Fibrotic Diseases. Curr. Med. Chem. 2017, 24(29): 3203-3215.
Xiao, S., Li, Q., Hu, L., Yu, Z., Yang, J., Chang, Q., Chen, Z., Hu, G. Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go? Mini Rev. Med. Chem. 2019, 19(18): 1544-1557.
Yu, Z., Chen, Z., Su, Q., Ye, S., Yuan, H., Kuai, M., Lv, M., Tu, Z., Yang, X., Liu, R., Hu, G., Li, Q. Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives. Bioorg. Med. Chem. 2019, 27(6): 944-954.
Huang, P., Le, X., Huang, F., Yang, J., Yang, H., Ma, J., Hu, G., Li, Q., Chen, Z. Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin. J. Med. Chem. 2020, 63(9): 4685-4700.
Hu, L., Zhao, R., Liu, Q., Li, Q. New Insights Into Heat Shock Protein 90 in the Pathogenesis of Pulmonary Arterial Hypertension. Front. Physiol. 2020, 11: 1081.
Hu, L., Li, L., Chang, Q., Fu, S., Qin, J., Chen, Z., Li, X., Liu, Q., Hu, G., Li, Q. Discovery of Novel Pyrazolo[3,4-b] Pyridine Derivatives with Dual Activities of Vascular Remodeling Inhibition and Vasodilation for the Treatment of Pulmonary Arterial Hypertension. J. Med. Chem. 2020, 63(19): 11215-11234.

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